microRNA-637/661 ameliorate hypoxic-induced pulmonary arterial hypertension by targeting TRIM29 signaling pathway

microRNA-637/661 ameliorate hypoxic-induced pulmonary arterial hypertension by targeting TRIM29 signaling pathway

Abstract The pathogenesis of pulmonary arterial hypertension (PAH) is closely linked to the abnormal proliferation of pulmonary artery smooth muscle cells. Studies have demonstrated that microRNAs play pivotal roles in the progression of pulmonary hypertension. We found that microRNA-637 (miR-637) a...

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Bibliographic Details
Main Authors: Liyang Jiang, Weiyi Tao, Jun Liu, Aixiang Yang, Jie Zhou
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Pulmonary arterial hypertension
microRNA
TRIM29
RNA-seq
AKT/mTOR signalling
Online Access:https://doi.org/10.1038/s41598-024-79769-2
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