Decoding Parkinson's Disease: The interplay of cell death pathways, oxidative stress, and therapeutic innovations

Decoding Parkinson's Disease: The interplay of cell death pathways, oxidative stress, and therapeutic innovations

Parkinson's disease (PD), a complex neurodegenerative disorder characterized by selective loss of substantia nigra (SN) dopaminergic neurons, pathological aggregation of α-synuclein (α-syn), and chronic neuroinflammation, is fundamentally driven by redox imbalance and oxidative stress. Recent s...

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Bibliographic Details
Main Authors: Tingting Liu, Xiangrui Kong, Junbo Qiao, Jianshe Wei
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Redox Biology
Subjects:
Apoptosis
Autophagy
Ferroptosis
Mitochondrial dysfunction
Glial cells
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231725003003
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