Lactation affects postweaning metabolic profiles, but not follicle size in multiparous sows
Young sows mobilise body reserves to support milk production during lactation, resulting in a negative energy balance (NEB). This NEB affects the development of follicles and oocytes that give rise to the next litter. Decreased IGF1 levels due to a NEB are thought to play a role in this process. As...
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Elsevier
2024-11-01
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| author | Q. Yu K.J. Teerds J. Keijer N.M. Soede |
| author_facet | Q. Yu K.J. Teerds J. Keijer N.M. Soede |
| author_sort | Q. Yu |
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| description | Young sows mobilise body reserves to support milk production during lactation, resulting in a negative energy balance (NEB). This NEB affects the development of follicles and oocytes that give rise to the next litter. Decreased IGF1 levels due to a NEB are thought to play a role in this process. As this has hardly been studied in multiparous sows, the current study focused on relations between lactation BW loss (%), metabolic hormones, and follicle development in multiparous sows at Day 0 and Day 4 after weaning. A total of 31 sows of parity 4.7 ± 2.5 were killed at either Day 0 or Day 4 after weaning. Average BW loss during lactation was 3.3 ± 4.5%, while average backfat loss was 4.1 ± 0.3 mm. The metabolic profile confirmed the metabolic impact of lactation as both non-esterified fatty acid (NEFA), and creatinine levels were higher at Day 0 than that at Day 4. Conversely, serum levels of IGF1 and growth differentiation factor 15 levels were lower on Day 0 than on Day 4. A higher BW loss (%) was related to higher NEFA levels on Day 0, but not on Day 4. IGF1 concentrations in serum and follicle fluid were similar at Day 0 and Day 4 and were not related to follicle size on these days. In conclusion, although lactation affected postweaning metabolic profiles in these multiparous sows, follicle size was not related to these profiles, probably due to the relatively mild BW loss of these sows. IGF1 concentrations were less affected by lactation and did not seem to limit follicle development, as it does in sows experiencing high weight loss. |
| format | Article |
| id | doaj-art-e013cb342d634e85ad4ea33d1f414dcc |
| institution | Kabale University |
| issn | 1751-7311 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Elsevier |
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| series | Animal |
| spelling | doaj-art-e013cb342d634e85ad4ea33d1f414dcc2024-11-16T05:10:27ZengElsevierAnimal1751-73112024-11-011811101339Lactation affects postweaning metabolic profiles, but not follicle size in multiparous sowsQ. Yu0K.J. Teerds1J. Keijer2N.M. Soede3Human and Animal Physiology, Department of Animal Sciences, Wageningen University, De Elst 1, 6708WD Wageningen, the NetherlandsHuman and Animal Physiology, Department of Animal Sciences, Wageningen University, De Elst 1, 6708WD Wageningen, the NetherlandsHuman and Animal Physiology, Department of Animal Sciences, Wageningen University, De Elst 1, 6708WD Wageningen, the NetherlandsAdaptation Physiology Group, Department of Animal Sciences, Wageningen University, De Elst 1, 6708WD Wageningen, the Netherlands; Corresponding author.Young sows mobilise body reserves to support milk production during lactation, resulting in a negative energy balance (NEB). This NEB affects the development of follicles and oocytes that give rise to the next litter. Decreased IGF1 levels due to a NEB are thought to play a role in this process. As this has hardly been studied in multiparous sows, the current study focused on relations between lactation BW loss (%), metabolic hormones, and follicle development in multiparous sows at Day 0 and Day 4 after weaning. A total of 31 sows of parity 4.7 ± 2.5 were killed at either Day 0 or Day 4 after weaning. Average BW loss during lactation was 3.3 ± 4.5%, while average backfat loss was 4.1 ± 0.3 mm. The metabolic profile confirmed the metabolic impact of lactation as both non-esterified fatty acid (NEFA), and creatinine levels were higher at Day 0 than that at Day 4. Conversely, serum levels of IGF1 and growth differentiation factor 15 levels were lower on Day 0 than on Day 4. A higher BW loss (%) was related to higher NEFA levels on Day 0, but not on Day 4. IGF1 concentrations in serum and follicle fluid were similar at Day 0 and Day 4 and were not related to follicle size on these days. In conclusion, although lactation affected postweaning metabolic profiles in these multiparous sows, follicle size was not related to these profiles, probably due to the relatively mild BW loss of these sows. IGF1 concentrations were less affected by lactation and did not seem to limit follicle development, as it does in sows experiencing high weight loss.http://www.sciencedirect.com/science/article/pii/S1751731124002763Follicular developmentGrowth differentiation factor 15IGF1Negative energy balancePig |
| spellingShingle | Q. Yu K.J. Teerds J. Keijer N.M. Soede Lactation affects postweaning metabolic profiles, but not follicle size in multiparous sows Animal Follicular development Growth differentiation factor 15 IGF1 Negative energy balance Pig |
| title | Lactation affects postweaning metabolic profiles, but not follicle size in multiparous sows |
| title_full | Lactation affects postweaning metabolic profiles, but not follicle size in multiparous sows |
| title_fullStr | Lactation affects postweaning metabolic profiles, but not follicle size in multiparous sows |
| title_full_unstemmed | Lactation affects postweaning metabolic profiles, but not follicle size in multiparous sows |
| title_short | Lactation affects postweaning metabolic profiles, but not follicle size in multiparous sows |
| title_sort | lactation affects postweaning metabolic profiles but not follicle size in multiparous sows |
| topic | Follicular development Growth differentiation factor 15 IGF1 Negative energy balance Pig |
| url | http://www.sciencedirect.com/science/article/pii/S1751731124002763 |
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