Evaluation of the Efficacy of Oxygen-releasing Gel as an Adjunct to Scaling and Root Planing in Chronic Periodontitis: A Split-mouth Randomized Controlled Trial
Background: The aim of the study was to clinically and microbiologically evaluate the efficacy of an oxygen-releasing gel as an adjunct to scaling and root planing (SRP) in chronic periodontitis. Materials and Methods: The study was in accordance with the ethical standards of the Indian Council of M...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-12-01
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| Series: | Journal of International Clinical Dental Research Organization |
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| Online Access: | https://journals.lww.com/10.4103/jicdro.jicdro_70_23 |
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| author | Shristi Agarwal Shweta Bali Priyanka Aggarwal Amit Garg Aruna Nautiyal Manish Sharma |
| author_facet | Shristi Agarwal Shweta Bali Priyanka Aggarwal Amit Garg Aruna Nautiyal Manish Sharma |
| author_sort | Shristi Agarwal |
| collection | DOAJ |
| description | Background:
The aim of the study was to clinically and microbiologically evaluate the efficacy of an oxygen-releasing gel as an adjunct to scaling and root planing (SRP) in chronic periodontitis.
Materials and Methods:
The study was in accordance with the ethical standards of the Indian Council of Medical Research. A total of selected 30 sites were divided into Group A (control) – SRP and Group B (Test) – SRP with oxygen-releasing gel. Plaque index (PI), gingival index (GI), pocket probing depth (PPD), and clinical attachment level (CAL) were recorded at baseline, 1, and 3 months. A plaque sample was sent for microbiological analysis (culture for colony count and polymerase chain reaction [PCR]) at baseline and 3 months. All Clinical and microbiological analysis were performed, and information was fed into an Excel® database for subsequent statistical analysis (SPSS 22.0).
Results:
A statistically significant difference in PI, GI, PPD, and CAL in both the groups was observed between baseline, 1, and 3 months (P < 0.05). Intergroup comparison showed a statistically higher significant reduction in PPD (3.60 ± 0.507 vs. 4.93 ± 0.594) and CAL ((3.60 ± 0.507 vs. 4.93 ± 0.594) in the test group when compared to the control group at 3 months from baseline. Reduction in colony count and PCR values of Porphyromonas gingivalis between baseline and 3 months was more in the test Group 3-month follow-up. However, no statistically significant difference was found in PI and GI between both groups.
Conclusion:
Oxygen-releasing gel, as an adjunct to SRP, is beneficial compared to scaling and root planning alone in chronic periodontitis. |
| format | Article |
| id | doaj-art-dffec988147c4d50b2b1f29fbe611f98 |
| institution | Kabale University |
| issn | 2231-0754 2231-5357 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of International Clinical Dental Research Organization |
| spelling | doaj-art-dffec988147c4d50b2b1f29fbe611f982025-01-12T10:37:26ZengWolters Kluwer Medknow PublicationsJournal of International Clinical Dental Research Organization2231-07542231-53572024-12-0116215716210.4103/jicdro.jicdro_70_23Evaluation of the Efficacy of Oxygen-releasing Gel as an Adjunct to Scaling and Root Planing in Chronic Periodontitis: A Split-mouth Randomized Controlled TrialShristi AgarwalShweta BaliPriyanka AggarwalAmit GargAruna NautiyalManish SharmaBackground: The aim of the study was to clinically and microbiologically evaluate the efficacy of an oxygen-releasing gel as an adjunct to scaling and root planing (SRP) in chronic periodontitis. Materials and Methods: The study was in accordance with the ethical standards of the Indian Council of Medical Research. A total of selected 30 sites were divided into Group A (control) – SRP and Group B (Test) – SRP with oxygen-releasing gel. Plaque index (PI), gingival index (GI), pocket probing depth (PPD), and clinical attachment level (CAL) were recorded at baseline, 1, and 3 months. A plaque sample was sent for microbiological analysis (culture for colony count and polymerase chain reaction [PCR]) at baseline and 3 months. All Clinical and microbiological analysis were performed, and information was fed into an Excel® database for subsequent statistical analysis (SPSS 22.0). Results: A statistically significant difference in PI, GI, PPD, and CAL in both the groups was observed between baseline, 1, and 3 months (P < 0.05). Intergroup comparison showed a statistically higher significant reduction in PPD (3.60 ± 0.507 vs. 4.93 ± 0.594) and CAL ((3.60 ± 0.507 vs. 4.93 ± 0.594) in the test group when compared to the control group at 3 months from baseline. Reduction in colony count and PCR values of Porphyromonas gingivalis between baseline and 3 months was more in the test Group 3-month follow-up. However, no statistically significant difference was found in PI and GI between both groups. Conclusion: Oxygen-releasing gel, as an adjunct to SRP, is beneficial compared to scaling and root planning alone in chronic periodontitis.https://journals.lww.com/10.4103/jicdro.jicdro_70_23chronic periodontitislocal drug deliveryoxygen-releasing gel |
| spellingShingle | Shristi Agarwal Shweta Bali Priyanka Aggarwal Amit Garg Aruna Nautiyal Manish Sharma Evaluation of the Efficacy of Oxygen-releasing Gel as an Adjunct to Scaling and Root Planing in Chronic Periodontitis: A Split-mouth Randomized Controlled Trial Journal of International Clinical Dental Research Organization chronic periodontitis local drug delivery oxygen-releasing gel |
| title | Evaluation of the Efficacy of Oxygen-releasing Gel as an Adjunct to Scaling and Root Planing in Chronic Periodontitis: A Split-mouth Randomized Controlled Trial |
| title_full | Evaluation of the Efficacy of Oxygen-releasing Gel as an Adjunct to Scaling and Root Planing in Chronic Periodontitis: A Split-mouth Randomized Controlled Trial |
| title_fullStr | Evaluation of the Efficacy of Oxygen-releasing Gel as an Adjunct to Scaling and Root Planing in Chronic Periodontitis: A Split-mouth Randomized Controlled Trial |
| title_full_unstemmed | Evaluation of the Efficacy of Oxygen-releasing Gel as an Adjunct to Scaling and Root Planing in Chronic Periodontitis: A Split-mouth Randomized Controlled Trial |
| title_short | Evaluation of the Efficacy of Oxygen-releasing Gel as an Adjunct to Scaling and Root Planing in Chronic Periodontitis: A Split-mouth Randomized Controlled Trial |
| title_sort | evaluation of the efficacy of oxygen releasing gel as an adjunct to scaling and root planing in chronic periodontitis a split mouth randomized controlled trial |
| topic | chronic periodontitis local drug delivery oxygen-releasing gel |
| url | https://journals.lww.com/10.4103/jicdro.jicdro_70_23 |
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