The Timing of Femur Fracture Fixation is an Important Factor for Prolonged Mechanical Ventilation
Purpose Mechanical ventilation (MV) is an essential life-saving modality for severely injured patients. However, the long-term use of MV is a major risk factor for late mortality. The surgical correction of long bone fractures plays a critical role not only in improving functional outcomes, but also...
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Korean Society of Traumatology
2019-12-01
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| Series: | Journal of Trauma and Injury |
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| Online Access: | http://www.jtraumainj.org/upload/pdf/jti-2019-028.pdf |
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| author | Hyung Chul Choi Kwang Hwan Jung Kyu Hyouck Kyoung Seong Ho Choi |
| author_facet | Hyung Chul Choi Kwang Hwan Jung Kyu Hyouck Kyoung Seong Ho Choi |
| author_sort | Hyung Chul Choi |
| collection | DOAJ |
| description | Purpose Mechanical ventilation (MV) is an essential life-saving modality for severely injured patients. However, the long-term use of MV is a major risk factor for late mortality. The surgical correction of long bone fractures plays a critical role not only in improving functional outcomes, but also in reducing physiological derangements, including MV duration. This study investigated the factors affecting prolonged MV (PMV) in severely injured patients with femur fractures. Methods We retrospectively evaluated all severely injured patients (injury severity score >15) with femur fractures who were taken to the emergency department within 12 hours of the causative accidents between January 2016 and December 2018. PMV was defined as MV lasting for ≥7 days. We analyzed the factors affecting PMV. Results In total, 35 patients were enrolled and 21 (33.3%) were included in the PMV group. The PMV group required more red blood cell (RBC) transfusions within 7 days RBC (7dRBC) (12.8 vs. 6.8 units; p=0.03) and the time to femur fracture fixation (TFFF) was longer (7.9 vs. 2.7 days; p=0.018). The area under the curve (AUC) for TFFF was 0.740 (95% confidence interval [CI]: 0.572–0.908; p=0.018) and the AUC for 7dRBC was 0.718 (95% CI: 0.546–0.889; p=0.031). Conclusions This study indicates that TFFF is an independent risk factor for PMV. Early fixation of femur fractures might prevent PMV and its associated complications. |
| format | Article |
| id | doaj-art-dfcd1b131a944f1ba2f64048c2a5ff8e |
| institution | Kabale University |
| issn | 1738-8767 2287-1683 |
| language | English |
| publishDate | 2019-12-01 |
| publisher | Korean Society of Traumatology |
| record_format | Article |
| series | Journal of Trauma and Injury |
| spelling | doaj-art-dfcd1b131a944f1ba2f64048c2a5ff8e2025-01-06T01:31:31ZengKorean Society of TraumatologyJournal of Trauma and Injury1738-87672287-16832019-12-0132422022510.20408/jti.2019.028995The Timing of Femur Fracture Fixation is an Important Factor for Prolonged Mechanical VentilationHyung Chul Choi0Kwang Hwan Jung1Kyu Hyouck Kyoung2Seong Ho Choi3 Department of Surgery, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea Department of Orthopedic Surgery, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea Department of Surgery, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea Department of Surgery, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, KoreaPurpose Mechanical ventilation (MV) is an essential life-saving modality for severely injured patients. However, the long-term use of MV is a major risk factor for late mortality. The surgical correction of long bone fractures plays a critical role not only in improving functional outcomes, but also in reducing physiological derangements, including MV duration. This study investigated the factors affecting prolonged MV (PMV) in severely injured patients with femur fractures. Methods We retrospectively evaluated all severely injured patients (injury severity score >15) with femur fractures who were taken to the emergency department within 12 hours of the causative accidents between January 2016 and December 2018. PMV was defined as MV lasting for ≥7 days. We analyzed the factors affecting PMV. Results In total, 35 patients were enrolled and 21 (33.3%) were included in the PMV group. The PMV group required more red blood cell (RBC) transfusions within 7 days RBC (7dRBC) (12.8 vs. 6.8 units; p=0.03) and the time to femur fracture fixation (TFFF) was longer (7.9 vs. 2.7 days; p=0.018). The area under the curve (AUC) for TFFF was 0.740 (95% confidence interval [CI]: 0.572–0.908; p=0.018) and the AUC for 7dRBC was 0.718 (95% CI: 0.546–0.889; p=0.031). Conclusions This study indicates that TFFF is an independent risk factor for PMV. Early fixation of femur fractures might prevent PMV and its associated complications.http://www.jtraumainj.org/upload/pdf/jti-2019-028.pdfmechanical ventilationfracture of long bonefixation of femoral fracture |
| spellingShingle | Hyung Chul Choi Kwang Hwan Jung Kyu Hyouck Kyoung Seong Ho Choi The Timing of Femur Fracture Fixation is an Important Factor for Prolonged Mechanical Ventilation Journal of Trauma and Injury mechanical ventilation fracture of long bone fixation of femoral fracture |
| title | The Timing of Femur Fracture Fixation is an Important Factor for Prolonged Mechanical Ventilation |
| title_full | The Timing of Femur Fracture Fixation is an Important Factor for Prolonged Mechanical Ventilation |
| title_fullStr | The Timing of Femur Fracture Fixation is an Important Factor for Prolonged Mechanical Ventilation |
| title_full_unstemmed | The Timing of Femur Fracture Fixation is an Important Factor for Prolonged Mechanical Ventilation |
| title_short | The Timing of Femur Fracture Fixation is an Important Factor for Prolonged Mechanical Ventilation |
| title_sort | timing of femur fracture fixation is an important factor for prolonged mechanical ventilation |
| topic | mechanical ventilation fracture of long bone fixation of femoral fracture |
| url | http://www.jtraumainj.org/upload/pdf/jti-2019-028.pdf |
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