Effect of high-density fat combined with adipose stem cell glue on the success rate of facial filling and its clinical value

Facial fat grafting is a popular cosmetic procedure, and experts are increasingly endorsing the use of high-density fat with adipose stem cell glue for better results. This study aims to explore the effect of high-density fat combined with adipose stem cell glue on the success rate of facial filling...

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Main Authors: Junsheng Xu, Yu Zhao
Format: Article
Language:English
Published: Medical Journals Sweden 2024-03-01
Series:Journal of Plastic Surgery and Hand Surgery
Subjects:
Online Access:https://medicaljournalssweden.se/JPHS/article/view/18683
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author Junsheng Xu
Yu Zhao
author_facet Junsheng Xu
Yu Zhao
author_sort Junsheng Xu
collection DOAJ
description Facial fat grafting is a popular cosmetic procedure, and experts are increasingly endorsing the use of high-density fat with adipose stem cell glue for better results. This study aims to explore the effect of high-density fat combined with adipose stem cell glue on the success rate of facial filling and its clinical value. We conducted a randomized trial with 100 patients who underwent facial fat transplantation between August 2020 and August 2022. They were divided into two groups: a control group receiving traditional Coleman fat transplantation and an observation group receiving high-density fat with adipose stem cells. In the observation and control groups, the excellent and good rate was 98.00 and 80.00%. After 3 months of treatment, the thickness of frontal subcutaneous fat and temporal subcutaneous fat in the observation group was higher (P < 0.05). Observation group retention of fat transplantation was noticeably higher 3 months after treatment (P < 0.05). Three months after treatment, the VISIA (facial imaging system) scores of facial color spots, facial pores and facial wrinkles in the observation group were lower (P < 0.05). After treatment, both groups indicated noticeable improvements in physiological functions, health status, social function, mental health, and somatic diseases compared to before treatment. Notably, the observation group had higher scores (P < 0.05). The observation group had a lower complication rate (4.00% vs. 22.00%) and higher satisfaction rate (98.00% vs. 86.00%) than the control group. Using high-density fat combined with adipose stem cell glue for facial fat grafting yields superior results, reduces complications, and boosts patient satisfaction compared to traditional methods. We have complied with all relevant ethical regulations with regard to the use of stem cells.
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spelling doaj-art-dfb7e47f9b5f45808452e8c98943a01c2025-08-25T11:16:45ZengMedical Journals SwedenJournal of Plastic Surgery and Hand Surgery2000-67642024-03-015910.2340/jphs.v59.18683Effect of high-density fat combined with adipose stem cell glue on the success rate of facial filling and its clinical valueJunsheng Xu0Yu Zhao1https://orcid.org/0009-0000-0575-2306Hefei BOE Hospital, Hefei City, Anhui Province, ChinaThe First Affiliated Hospital of Anhui Medical University, Hefei City, Anhui Province, ChinaFacial fat grafting is a popular cosmetic procedure, and experts are increasingly endorsing the use of high-density fat with adipose stem cell glue for better results. This study aims to explore the effect of high-density fat combined with adipose stem cell glue on the success rate of facial filling and its clinical value. We conducted a randomized trial with 100 patients who underwent facial fat transplantation between August 2020 and August 2022. They were divided into two groups: a control group receiving traditional Coleman fat transplantation and an observation group receiving high-density fat with adipose stem cells. In the observation and control groups, the excellent and good rate was 98.00 and 80.00%. After 3 months of treatment, the thickness of frontal subcutaneous fat and temporal subcutaneous fat in the observation group was higher (P < 0.05). Observation group retention of fat transplantation was noticeably higher 3 months after treatment (P < 0.05). Three months after treatment, the VISIA (facial imaging system) scores of facial color spots, facial pores and facial wrinkles in the observation group were lower (P < 0.05). After treatment, both groups indicated noticeable improvements in physiological functions, health status, social function, mental health, and somatic diseases compared to before treatment. Notably, the observation group had higher scores (P < 0.05). The observation group had a lower complication rate (4.00% vs. 22.00%) and higher satisfaction rate (98.00% vs. 86.00%) than the control group. Using high-density fat combined with adipose stem cell glue for facial fat grafting yields superior results, reduces complications, and boosts patient satisfaction compared to traditional methods. We have complied with all relevant ethical regulations with regard to the use of stem cells. https://medicaljournalssweden.se/JPHS/article/view/18683High density fatAdipose stem cell glueSuccess rate of facial fillingLife qualityComplications
spellingShingle Junsheng Xu
Yu Zhao
Effect of high-density fat combined with adipose stem cell glue on the success rate of facial filling and its clinical value
Journal of Plastic Surgery and Hand Surgery
High density fat
Adipose stem cell glue
Success rate of facial filling
Life quality
Complications
title Effect of high-density fat combined with adipose stem cell glue on the success rate of facial filling and its clinical value
title_full Effect of high-density fat combined with adipose stem cell glue on the success rate of facial filling and its clinical value
title_fullStr Effect of high-density fat combined with adipose stem cell glue on the success rate of facial filling and its clinical value
title_full_unstemmed Effect of high-density fat combined with adipose stem cell glue on the success rate of facial filling and its clinical value
title_short Effect of high-density fat combined with adipose stem cell glue on the success rate of facial filling and its clinical value
title_sort effect of high density fat combined with adipose stem cell glue on the success rate of facial filling and its clinical value
topic High density fat
Adipose stem cell glue
Success rate of facial filling
Life quality
Complications
url https://medicaljournalssweden.se/JPHS/article/view/18683
work_keys_str_mv AT junshengxu effectofhighdensityfatcombinedwithadiposestemcellglueonthesuccessrateoffacialfillinganditsclinicalvalue
AT yuzhao effectofhighdensityfatcombinedwithadiposestemcellglueonthesuccessrateoffacialfillinganditsclinicalvalue