Prediction of protein–protein interaction based on interaction-specific learning and hierarchical information

Prediction of protein–protein interaction based on interaction-specific learning and hierarchical information

Abstract Background Prediction of protein–protein interactions (PPIs) is fundamental for identifying drug targets and understanding cellular processes. The rapid growth of PPI studies necessitates the development of efficient and accurate tools for automated prediction of PPIs. In recent years, seve...

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Bibliographic Details
Main Authors: Tao Tang, Taiguang Shen, Jing Jiang, Weizhuo Li, Peng Wang, Sisi Yuan, Xiaofeng Cao, Yuansheng Liu
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Biology
Subjects:
Protein–protein interactions
Deep learning
Interaction-specific learning
Hyperbolic space
Online Access:https://doi.org/10.1186/s12915-025-02359-9
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