A Case of Visceral Leishmaniasis Characterized by Fever of Unknown Origin and Nodular Lesions in the Spleen
Introduction: Leishmaniasis is a zoonosis caused by Leishmania spp. parasites through the bite of infected female sandflies and has three main forms: visceral (VL), cutaneous (CL) and mucocutaneous (MCL). VL is endemic in many countries around the world. It is on the World H...
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Selcuk University Press
2024-06-01
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| Series: | Genel Tıp Dergisi |
| Online Access: | https://dergipark.org.tr/tr/doi/10.54005/geneltip.1406185 |
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| author | Yakup Gezer Erol Handemir Arzu Tarakçı Muhammet Rıdvan Tayşi A Basturk Salih Cırık |
| author_facet | Yakup Gezer Erol Handemir Arzu Tarakçı Muhammet Rıdvan Tayşi A Basturk Salih Cırık |
| author_sort | Yakup Gezer |
| collection | DOAJ |
| description |
Introduction: Leishmaniasis is a zoonosis caused by Leishmania spp. parasites through the bite of infected female sandflies and has three main forms: visceral (VL), cutaneous (CL) and mucocutaneous (MCL). VL is endemic in many countries around the world. It is on the World Health Organisation's (WHO) list of neglected diseases and is difficult to diagnose due to its non-specific clinical manifestations. VL is characterised by fever, hepatosplenomegaly and bone marrow suppression. The diagnosis is made by the presence of amastigotes in tissue or blood samples or serological and DNA-based techniques. Case: Our patient was a 30-year-old male did not have any immunodeficiency. He was characterised by persistent fever, pancytopenia, hepatosplenomegaly and multiple millimetric hypoechoic solid nodules in the spleen. The diagnosis of VL was confirmed using all three parasitological, serological and molecular methods. Cure was achieved by treatment with liposomal amphotericin B (L-AmB). Discussion: VL should be considered in the differential diagnosis of patients with fever of unknown cause, pancytopenia and hepatosplenomegaly. The presence of solid nodular lesions in the spleen may also shed light in favour of VL |
| format | Article |
| id | doaj-art-deee5af7588b426a96888458eb4a2ceb |
| institution | Kabale University |
| issn | 2602-3741 |
| language | English |
| publishDate | 2024-06-01 |
| publisher | Selcuk University Press |
| record_format | Article |
| series | Genel Tıp Dergisi |
| spelling | doaj-art-deee5af7588b426a96888458eb4a2ceb2024-12-02T08:09:58ZengSelcuk University PressGenel Tıp Dergisi2602-37412024-06-0134341641810.54005/geneltip.1406185 A Case of Visceral Leishmaniasis Characterized by Fever of Unknown Origin and Nodular Lesions in the Spleen Yakup Gezer0https://orcid.org/0000-0002-1582-7313Erol Handemir1https://orcid.org/0000-0003-0094-8507Arzu Tarakçı2https://orcid.org/0000-0002-1245-3221Muhammet Rıdvan Tayşi3https://orcid.org/0000-0002-2609-264XA Basturk4https://orcid.org/0000-0003-1864-0316Salih Cırık5https://orcid.org/0000-0002-1368-7919Sağlık Bilimleri Üniversitesi Konya Şehir HastanesiKonya İl Sağlık Müdürlüğü Halk Sağlığı Hizmetleri Başkanlığı, Bulaşıcı Hastalıklar BirimiSağlık Bilimleri Üniversitesi Konya Şehir HastanesiSağlık Bilimleri Üniversitesi Konya Şehir HastanesiSağlık Bilimleri Üniversitesi Konya Şehir HastanesiSağlık Bilimleri Üniversitesi Konya Şehir Hastanesi Introduction: Leishmaniasis is a zoonosis caused by Leishmania spp. parasites through the bite of infected female sandflies and has three main forms: visceral (VL), cutaneous (CL) and mucocutaneous (MCL). VL is endemic in many countries around the world. It is on the World Health Organisation's (WHO) list of neglected diseases and is difficult to diagnose due to its non-specific clinical manifestations. VL is characterised by fever, hepatosplenomegaly and bone marrow suppression. The diagnosis is made by the presence of amastigotes in tissue or blood samples or serological and DNA-based techniques. Case: Our patient was a 30-year-old male did not have any immunodeficiency. He was characterised by persistent fever, pancytopenia, hepatosplenomegaly and multiple millimetric hypoechoic solid nodules in the spleen. The diagnosis of VL was confirmed using all three parasitological, serological and molecular methods. Cure was achieved by treatment with liposomal amphotericin B (L-AmB). Discussion: VL should be considered in the differential diagnosis of patients with fever of unknown cause, pancytopenia and hepatosplenomegaly. The presence of solid nodular lesions in the spleen may also shed light in favour of VLhttps://dergipark.org.tr/tr/doi/10.54005/geneltip.1406185 |
| spellingShingle | Yakup Gezer Erol Handemir Arzu Tarakçı Muhammet Rıdvan Tayşi A Basturk Salih Cırık A Case of Visceral Leishmaniasis Characterized by Fever of Unknown Origin and Nodular Lesions in the Spleen Genel Tıp Dergisi |
| title |
A Case of Visceral Leishmaniasis Characterized by Fever of Unknown Origin and Nodular Lesions in the Spleen
|
| title_full |
A Case of Visceral Leishmaniasis Characterized by Fever of Unknown Origin and Nodular Lesions in the Spleen
|
| title_fullStr |
A Case of Visceral Leishmaniasis Characterized by Fever of Unknown Origin and Nodular Lesions in the Spleen
|
| title_full_unstemmed |
A Case of Visceral Leishmaniasis Characterized by Fever of Unknown Origin and Nodular Lesions in the Spleen
|
| title_short |
A Case of Visceral Leishmaniasis Characterized by Fever of Unknown Origin and Nodular Lesions in the Spleen
|
| title_sort | case of visceral leishmaniasis characterized by fever of unknown origin and nodular lesions in the spleen |
| url | https://dergipark.org.tr/tr/doi/10.54005/geneltip.1406185 |
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