Structural constraints on the emergence of oscillations in multi-population neural networks

Oscillations arise in many real-world systems and are associated with both functional and dysfunctional states. Whether a network can oscillate can be estimated if we know the strength of interaction between nodes. But in real-world networks (in particular in biological networks) it is usually not p...

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Main Authors: Jie Zang, Shenquan Liu, Pascal Helson, Arvind Kumar
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-03-01
Series:eLife
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Online Access:https://elifesciences.org/articles/88777
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author Jie Zang
Shenquan Liu
Pascal Helson
Arvind Kumar
author_facet Jie Zang
Shenquan Liu
Pascal Helson
Arvind Kumar
author_sort Jie Zang
collection DOAJ
description Oscillations arise in many real-world systems and are associated with both functional and dysfunctional states. Whether a network can oscillate can be estimated if we know the strength of interaction between nodes. But in real-world networks (in particular in biological networks) it is usually not possible to know the exact connection weights. Therefore, it is important to determine the structural properties of a network necessary to generate oscillations. Here, we provide a proof that uses dynamical system theory to prove that an odd number of inhibitory nodes and strong enough connections are necessary to generate oscillations in a single cycle threshold-linear network. We illustrate these analytical results in a biologically plausible network with either firing-rate based or spiking neurons. Our work provides structural properties necessary to generate oscillations in a network. We use this knowledge to reconcile recent experimental findings about oscillations in basal ganglia with classical findings.
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spelling doaj-art-deae3bd1462842d28bd24e33e56fc8f12024-11-11T14:47:11ZengeLife Sciences Publications LtdeLife2050-084X2024-03-011210.7554/eLife.88777Structural constraints on the emergence of oscillations in multi-population neural networksJie Zang0https://orcid.org/0000-0003-2655-3343Shenquan Liu1Pascal Helson2https://orcid.org/0000-0002-2877-3705Arvind Kumar3https://orcid.org/0000-0002-8044-9195School of Mathematics, South China University of Technology, Guangzhou, China; Division of Computational Science and Technology, School of Electrical Engineering and Computer Science, KTH Royal Institute of Technology, Stockholm, SwedenSchool of Mathematics, South China University of Technology, Guangzhou, ChinaDivision of Computational Science and Technology, School of Electrical Engineering and Computer Science, KTH Royal Institute of Technology, Stockholm, Sweden; Science for Life Laboratory, Stockholm, SwedenDivision of Computational Science and Technology, School of Electrical Engineering and Computer Science, KTH Royal Institute of Technology, Stockholm, Sweden; Science for Life Laboratory, Stockholm, SwedenOscillations arise in many real-world systems and are associated with both functional and dysfunctional states. Whether a network can oscillate can be estimated if we know the strength of interaction between nodes. But in real-world networks (in particular in biological networks) it is usually not possible to know the exact connection weights. Therefore, it is important to determine the structural properties of a network necessary to generate oscillations. Here, we provide a proof that uses dynamical system theory to prove that an odd number of inhibitory nodes and strong enough connections are necessary to generate oscillations in a single cycle threshold-linear network. We illustrate these analytical results in a biologically plausible network with either firing-rate based or spiking neurons. Our work provides structural properties necessary to generate oscillations in a network. We use this knowledge to reconcile recent experimental findings about oscillations in basal ganglia with classical findings.https://elifesciences.org/articles/88777oscillationsneural networksbasal ganglianetwork structurenetwork dynamics
spellingShingle Jie Zang
Shenquan Liu
Pascal Helson
Arvind Kumar
Structural constraints on the emergence of oscillations in multi-population neural networks
eLife
oscillations
neural networks
basal ganglia
network structure
network dynamics
title Structural constraints on the emergence of oscillations in multi-population neural networks
title_full Structural constraints on the emergence of oscillations in multi-population neural networks
title_fullStr Structural constraints on the emergence of oscillations in multi-population neural networks
title_full_unstemmed Structural constraints on the emergence of oscillations in multi-population neural networks
title_short Structural constraints on the emergence of oscillations in multi-population neural networks
title_sort structural constraints on the emergence of oscillations in multi population neural networks
topic oscillations
neural networks
basal ganglia
network structure
network dynamics
url https://elifesciences.org/articles/88777
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AT shenquanliu structuralconstraintsontheemergenceofoscillationsinmultipopulationneuralnetworks
AT pascalhelson structuralconstraintsontheemergenceofoscillationsinmultipopulationneuralnetworks
AT arvindkumar structuralconstraintsontheemergenceofoscillationsinmultipopulationneuralnetworks