Photodynamic therapy for male genital lichen sclerosus with urethral stricture—Case report
Male genital lichen sclerosus (MGLSc) typically impacts the external genitalia, resulting in balanitis, erectile pain, urination symptoms, and/or urinary retention. Urethral stricture develops in up to 20 % of these patients, which is usually found in the distal part of the urethra but can, in sever...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-02-01
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| Series: | Photodiagnosis and Photodynamic Therapy |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1572100023006762 |
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| author | Nan Hu Yongzhen Zou Xun Deng Lian Zhang Zhifang Zhai Rui Yin |
| author_facet | Nan Hu Yongzhen Zou Xun Deng Lian Zhang Zhifang Zhai Rui Yin |
| author_sort | Nan Hu |
| collection | DOAJ |
| description | Male genital lichen sclerosus (MGLSc) typically impacts the external genitalia, resulting in balanitis, erectile pain, urination symptoms, and/or urinary retention. Urethral stricture develops in up to 20 % of these patients, which is usually found in the distal part of the urethra but can, in severe instances, impact the entire urethra and cause structural changes. Patients with skin lesions limited to the foreskin and partially extending to the glans can typically be cured by circumcision, but the recurrence rate of stricture is high when the glans or urethra is extensively involved. In the following case report, we describe a 45-year-old man with a history of MGLSc for 3 years and urethral stricture for 2 years, and these conditions remained untreated after circumcision. We emphasize that treatment with 5-aminolevulinic acid-induced photodynamic therapy (ALA-PDT) may further improve outcomes in such severe cases. |
| format | Article |
| id | doaj-art-de77c74efcab46a3a23628b4dbfe8921 |
| institution | Kabale University |
| issn | 1572-1000 |
| language | English |
| publishDate | 2024-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Photodiagnosis and Photodynamic Therapy |
| spelling | doaj-art-de77c74efcab46a3a23628b4dbfe89212024-12-11T05:55:27ZengElsevierPhotodiagnosis and Photodynamic Therapy1572-10002024-02-0145103947Photodynamic therapy for male genital lichen sclerosus with urethral stricture—Case reportNan Hu0Yongzhen Zou1Xun Deng2Lian Zhang3Zhifang Zhai4Rui Yin5Department of Dermatology, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, ChinaDepartment of Dermatology, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, ChinaDepartment of Dermatology, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, ChinaDepartment of Dermatology, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, ChinaDepartment of Dermatology, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, ChinaCorresponding author.; Department of Dermatology, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, ChinaMale genital lichen sclerosus (MGLSc) typically impacts the external genitalia, resulting in balanitis, erectile pain, urination symptoms, and/or urinary retention. Urethral stricture develops in up to 20 % of these patients, which is usually found in the distal part of the urethra but can, in severe instances, impact the entire urethra and cause structural changes. Patients with skin lesions limited to the foreskin and partially extending to the glans can typically be cured by circumcision, but the recurrence rate of stricture is high when the glans or urethra is extensively involved. In the following case report, we describe a 45-year-old man with a history of MGLSc for 3 years and urethral stricture for 2 years, and these conditions remained untreated after circumcision. We emphasize that treatment with 5-aminolevulinic acid-induced photodynamic therapy (ALA-PDT) may further improve outcomes in such severe cases.http://www.sciencedirect.com/science/article/pii/S1572100023006762Male genital lichen sclerosusUrethral stricture5-aminolevulinic acidPhotodynamic therapy |
| spellingShingle | Nan Hu Yongzhen Zou Xun Deng Lian Zhang Zhifang Zhai Rui Yin Photodynamic therapy for male genital lichen sclerosus with urethral stricture—Case report Photodiagnosis and Photodynamic Therapy Male genital lichen sclerosus Urethral stricture 5-aminolevulinic acid Photodynamic therapy |
| title | Photodynamic therapy for male genital lichen sclerosus with urethral stricture—Case report |
| title_full | Photodynamic therapy for male genital lichen sclerosus with urethral stricture—Case report |
| title_fullStr | Photodynamic therapy for male genital lichen sclerosus with urethral stricture—Case report |
| title_full_unstemmed | Photodynamic therapy for male genital lichen sclerosus with urethral stricture—Case report |
| title_short | Photodynamic therapy for male genital lichen sclerosus with urethral stricture—Case report |
| title_sort | photodynamic therapy for male genital lichen sclerosus with urethral stricture case report |
| topic | Male genital lichen sclerosus Urethral stricture 5-aminolevulinic acid Photodynamic therapy |
| url | http://www.sciencedirect.com/science/article/pii/S1572100023006762 |
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