Biofilm-mediated antibiotic tolerance in Staphylococcus aureus from spinal cord stimulation device-related infections

Biofilm-mediated antibiotic tolerance in Staphylococcus aureus from spinal cord stimulation device-related infections

ABSTRACT Staphylococcus aureus is a predominant cause of infections in individuals with spinal cord stimulation (SCS) devices. Biofilm formation complicates these infections, commonly requiring both surgical and antibiotic treatments. This study explored the biofilm matrix composition and antimicrob...

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Main Authors: Francesca Sivori, Ilaria Cavallo, Mauro Truglio, Lorella Pelagalli, Valerio Mariani, Giorgia Fabrizio, Elva Abril, Iolanda Santino, Piera Assunta Fradiani, Mariacarmela Solmone, Fulvia Pimpinelli, Luigi Toma, Roberto Arcioni, Roberto Alberto De Blasi, Enea Gino Di Domenico
Format: Article
Language:English
Published: American Society for Microbiology 2024-12-01
Series:Microbiology Spectrum
Subjects:
biofilm
spinal cord stimulation
Staphylococcus aureus
vancomycin
oxacillin
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01683-24
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