New possibilities of using methylaethylpiridinolum in ophthalmological practice
<b><br> </b><br> E.A. Egorov<sup>1</sup>, A.A. Gvetadze<sup>2<br> </sup><br> <sup>1</sup> Pirogov Russian National Research Medical University, Moscow, Russian Federation<br> <sup>2</sup> City Clinical Hos...
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| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Prime-Media
2019-01-01
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| Series: | РМЖ "Клиническая офтальмология" |
| Online Access: | http://clinopht.com/upload/iblock/5e1/5e13d4a891e6b112391f0417060321a1.pdf |
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E.A. Egorov<sup>1</sup>, A.A. Gvetadze<sup>2<br>
</sup><br>
<sup>1</sup> Pirogov Russian National Research Medical University, Moscow, Russian Federation<br>
<sup>2</sup> City Clinical Hospital No. 15, Moscow, Russian Federation<br>
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It is known that oxidative stress (OS) is an integral part of the pathophysiological chain in the development of many eye diseases. The most dangerous part of the OS is the formation of reactive oxygen species (ROS), capable of causing defects in many cellular components. The ROS formation is constant and occurs mainly in the mitochondria, but their level is normally low and inactivated by the antioxidant system. <br>
For ophthalmologists, the most interesting is the mechanism of ROS formation in the tissues of the eyeball (retina, lens, cornea, etc.). A review of the literature confirms the effect of OS on the development of glaucoma, diabetic retinopathy, and age-related macular degeneration. <br>
An important problem is the treatment of eye diseases in terms of OS suppression, correction of metabolic disorders and angioprotection. <br>
At present, drugs with antioxidant and angioprotective properties have become widely used in ophthalmological clinical practice. Information is provided on the use of methylaethylpiridinolum antioxidant in the prevention and treatment of eye diseases. An important part in the review is given to the results of clinical studies that prove the efficacy and safety of methylaethylpiridinolum in ophthalmological practice.<br>
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<b>Key words:</b> oxidative stress, reactive oxygen species, methylaethylpiridinolum, antioxidant, sodium hyaluronate, retinoprotection, diabetic retinopathy, glaucoma, age-related macular degeneration.<br>
<b>For citation:</b> Egorov E.A., Gvetadze A.A. New possibilities of using methylaethylpiridinolum in ophthalmological practice. RMJ “Clinical ophthalmology”. 2018;4:190–192.<br> |
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| ISSN: | 2311-7729 2619-1571 |