降钙素受体基因多态性与老年男性骨密度关系
[目的]探讨降钙素受体基因(CTR)C1377T基因多态性与老年男性人群骨密度相互关系.[方法]选取年龄≥65岁广州地区汉族男性个体247例,采用双能X线吸收法(DEXA)测定其全身、腰椎2~4(L2~4)、股骨颈(Neck)、粗隆间(Inter)、Ward'三角和大转子(Troch)区等部位的骨密度(BMD)值,并采用聚合酶链反应限制性片段长度多态性(PCR-RFLP)技术检测外周血白细胞基因组降钙素受体基因多态性.[结果]247例受试对象中,CTR基因型分别为CC型205例(83.0%),CT型39例(15.8%),TT型3例(1.2%);基因频率CC型为90.9%,TT型为9.1%,基因...
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Main Authors: | 李东风, 蔡雪珍, 杨燕红, 吴文, 黄小穗, 董婷, 林凯, 智喜梅 |
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Format: | Article |
Language: | zho |
Published: |
Editorial Office of Journal of Sun Yat-sen University
2006-01-01
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Series: | Zhongshan Daxue xuebao. Yixue kexue ban |
Subjects: | |
Online Access: | http://xuebaoyx.sysu.edu.cn/zh/article/43583010/ |
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