Update on the pathophysiology and management of acute trauma hemorrhage and trauma-induced coagulopathy based upon viscoelastic testing
Uncontrolled hemorrhage and trauma-induced coagulopathy (TIC) are the two predominant causes of preventable death after trauma. Early control of bleeding sources and rapid detection, characterization and management of TIC have been associated with improved outcomes. However, recent surveys confirm v...
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| Format: | Article |
| Language: | English |
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The Korean Society of Emergency Medicine
2024-09-01
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| Series: | Clinical and Experimental Emergency Medicine |
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| Online Access: | http://www.ceemjournal.org/upload/pdf/ceem-24-202.pdf |
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| _version_ | 1846163797001109504 |
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| author | Marc Maegele |
| author_facet | Marc Maegele |
| author_sort | Marc Maegele |
| collection | DOAJ |
| description | Uncontrolled hemorrhage and trauma-induced coagulopathy (TIC) are the two predominant causes of preventable death after trauma. Early control of bleeding sources and rapid detection, characterization and management of TIC have been associated with improved outcomes. However, recent surveys confirm vast heterogeneity in the clinical diagnosis and management of hemorrhage and TIC from acute trauma, even in advanced trauma centers. In addition, conventional coagulation assays, although still used frequently during the early assessment of bleeding trauma patients, have their limitations. This narrative review highlights the clinical value of rapid point-of-care viscoelastic testing for the early diagnosis and individualized goal-directed therapy in bleeding trauma patients with TIC. |
| format | Article |
| id | doaj-art-de25d128e4764ae3a762bec4cb2f36fc |
| institution | Kabale University |
| issn | 2383-4625 |
| language | English |
| publishDate | 2024-09-01 |
| publisher | The Korean Society of Emergency Medicine |
| record_format | Article |
| series | Clinical and Experimental Emergency Medicine |
| spelling | doaj-art-de25d128e4764ae3a762bec4cb2f36fc2024-11-19T00:09:27ZengThe Korean Society of Emergency MedicineClinical and Experimental Emergency Medicine2383-46252024-09-0111325926710.15441/ceem.24.202546Update on the pathophysiology and management of acute trauma hemorrhage and trauma-induced coagulopathy based upon viscoelastic testingMarc Maegele0 Department of Trauma and Orthopedic Surgery, Cologne-Merheim Medical Center (CMMC), Witten/Herdecke University, Cologne, GermanyUncontrolled hemorrhage and trauma-induced coagulopathy (TIC) are the two predominant causes of preventable death after trauma. Early control of bleeding sources and rapid detection, characterization and management of TIC have been associated with improved outcomes. However, recent surveys confirm vast heterogeneity in the clinical diagnosis and management of hemorrhage and TIC from acute trauma, even in advanced trauma centers. In addition, conventional coagulation assays, although still used frequently during the early assessment of bleeding trauma patients, have their limitations. This narrative review highlights the clinical value of rapid point-of-care viscoelastic testing for the early diagnosis and individualized goal-directed therapy in bleeding trauma patients with TIC.http://www.ceemjournal.org/upload/pdf/ceem-24-202.pdftraumableedinghemorrhagecoagulopathyviscoelastic testing |
| spellingShingle | Marc Maegele Update on the pathophysiology and management of acute trauma hemorrhage and trauma-induced coagulopathy based upon viscoelastic testing Clinical and Experimental Emergency Medicine trauma bleeding hemorrhage coagulopathy viscoelastic testing |
| title | Update on the pathophysiology and management of acute trauma hemorrhage and trauma-induced coagulopathy based upon viscoelastic testing |
| title_full | Update on the pathophysiology and management of acute trauma hemorrhage and trauma-induced coagulopathy based upon viscoelastic testing |
| title_fullStr | Update on the pathophysiology and management of acute trauma hemorrhage and trauma-induced coagulopathy based upon viscoelastic testing |
| title_full_unstemmed | Update on the pathophysiology and management of acute trauma hemorrhage and trauma-induced coagulopathy based upon viscoelastic testing |
| title_short | Update on the pathophysiology and management of acute trauma hemorrhage and trauma-induced coagulopathy based upon viscoelastic testing |
| title_sort | update on the pathophysiology and management of acute trauma hemorrhage and trauma induced coagulopathy based upon viscoelastic testing |
| topic | trauma bleeding hemorrhage coagulopathy viscoelastic testing |
| url | http://www.ceemjournal.org/upload/pdf/ceem-24-202.pdf |
| work_keys_str_mv | AT marcmaegele updateonthepathophysiologyandmanagementofacutetraumahemorrhageandtraumainducedcoagulopathybaseduponviscoelastictesting |