Spatiotemporal-controllable ROS-responsive camptothecin nano-bomb for chemo/photo/immunotherapy in triple-negative breast cancer

Spatiotemporal-controllable ROS-responsive camptothecin nano-bomb for chemo/photo/immunotherapy in triple-negative breast cancer

Abstract Chemotherapy is still one of the major approaches in triple-negative breast cancer (TNBC) treatment. The development of new formulations for classic chemotherapeutic drugs remains interests in studies. Camptothecin (CPT) is powerful antitumor agents in TNBC treatment though its clinic appli...

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Bibliographic Details
Main Authors: Wenjie Xu, Zhaokui Zeng, Yucheng Tang, Jingjing Tian, Xinyan Hao, Pengcheng Sun, Yanjin Peng, Tian Tian, Daxiong Xiang, Rongrong Wang, Chuanpin Chen, Junyong Wu
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Journal of Nanobiotechnology
Subjects:
Spatiotemporal-controllable
Self-assembly
ROS-responsive prodrug
Combination therapy
ICD
Anti-metastasis
Online Access:https://doi.org/10.1186/s12951-024-03050-x
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