Biophysical mechanism of animal magnetoreception, orientation and navigation

Abstract We describe a biophysical mechanism for animal magnetoreception, orientation and navigation in the geomagnetic field (GMF), based on the ion forced oscillation (IFO) mechanism in animal cell membrane voltage-gated ion channels (VGICs) (IFO-VGIC mechanism). We review previously suggested hyp...

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Main Authors: Dimitris J. Panagopoulos, Andreas Karabarbounis, George P. Chrousos
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-024-77883-9
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author Dimitris J. Panagopoulos
Andreas Karabarbounis
George P. Chrousos
author_facet Dimitris J. Panagopoulos
Andreas Karabarbounis
George P. Chrousos
author_sort Dimitris J. Panagopoulos
collection DOAJ
description Abstract We describe a biophysical mechanism for animal magnetoreception, orientation and navigation in the geomagnetic field (GMF), based on the ion forced oscillation (IFO) mechanism in animal cell membrane voltage-gated ion channels (VGICs) (IFO-VGIC mechanism). We review previously suggested hypotheses. We describe the structure and function of VGICs and argue that they are the most sensitive electromagnetic sensors in all animals. We consider the magnetic force exerted by the GMF on a mobile ion within a VGIC of an animal with periodic velocity variation. We apply this force in the IFO equation resulting in solution connecting the GMF intensity with the velocity variation rate. We show that animals with periodic velocity variations, receive oscillating forces on their mobile ions within VGICs, which are forced to oscillate exerting forces on the voltage sensors of the channels, similar or greater to the forces from membrane voltage changes that normally induce gating. Thus, the GMF in combination with the varying animal velocity can gate VGICs and alter cell homeostasis in a degree depending, for a given velocity and velocity variation rate, on GMF intensity (unique in each latitude) and the angle between velocity and GMF axis, which determine animal position and orientation.
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spelling doaj-art-ddc74cf76b114c81b89dcc789e74b50e2024-12-08T12:27:12ZengNature PortfolioScientific Reports2045-23222024-12-0114111610.1038/s41598-024-77883-9Biophysical mechanism of animal magnetoreception, orientation and navigationDimitris J. Panagopoulos0Andreas Karabarbounis1George P. Chrousos2Choremeion Research Laboratory, 1st Department of Paediatrics, Medical School, National and Kapodistrian University of AthensDepartment of Physics, Section of Nuclear and Particle Physics, National and Kapodistrian University of AthensChoremeion Research Laboratory, 1st Department of Paediatrics, Medical School, National and Kapodistrian University of AthensAbstract We describe a biophysical mechanism for animal magnetoreception, orientation and navigation in the geomagnetic field (GMF), based on the ion forced oscillation (IFO) mechanism in animal cell membrane voltage-gated ion channels (VGICs) (IFO-VGIC mechanism). We review previously suggested hypotheses. We describe the structure and function of VGICs and argue that they are the most sensitive electromagnetic sensors in all animals. We consider the magnetic force exerted by the GMF on a mobile ion within a VGIC of an animal with periodic velocity variation. We apply this force in the IFO equation resulting in solution connecting the GMF intensity with the velocity variation rate. We show that animals with periodic velocity variations, receive oscillating forces on their mobile ions within VGICs, which are forced to oscillate exerting forces on the voltage sensors of the channels, similar or greater to the forces from membrane voltage changes that normally induce gating. Thus, the GMF in combination with the varying animal velocity can gate VGICs and alter cell homeostasis in a degree depending, for a given velocity and velocity variation rate, on GMF intensity (unique in each latitude) and the angle between velocity and GMF axis, which determine animal position and orientation.https://doi.org/10.1038/s41598-024-77883-9Geomagnetic fieldAnimal magnetoreceptionOrientationNavigationElectromagnetic fieldsVoltage-gated ion channels
spellingShingle Dimitris J. Panagopoulos
Andreas Karabarbounis
George P. Chrousos
Biophysical mechanism of animal magnetoreception, orientation and navigation
Scientific Reports
Geomagnetic field
Animal magnetoreception
Orientation
Navigation
Electromagnetic fields
Voltage-gated ion channels
title Biophysical mechanism of animal magnetoreception, orientation and navigation
title_full Biophysical mechanism of animal magnetoreception, orientation and navigation
title_fullStr Biophysical mechanism of animal magnetoreception, orientation and navigation
title_full_unstemmed Biophysical mechanism of animal magnetoreception, orientation and navigation
title_short Biophysical mechanism of animal magnetoreception, orientation and navigation
title_sort biophysical mechanism of animal magnetoreception orientation and navigation
topic Geomagnetic field
Animal magnetoreception
Orientation
Navigation
Electromagnetic fields
Voltage-gated ion channels
url https://doi.org/10.1038/s41598-024-77883-9
work_keys_str_mv AT dimitrisjpanagopoulos biophysicalmechanismofanimalmagnetoreceptionorientationandnavigation
AT andreaskarabarbounis biophysicalmechanismofanimalmagnetoreceptionorientationandnavigation
AT georgepchrousos biophysicalmechanismofanimalmagnetoreceptionorientationandnavigation