Development of a novel multi-epitope subunit mRNA vaccine candidate to combat Acinetobacter baumannii

Development of a novel multi-epitope subunit mRNA vaccine candidate to combat Acinetobacter baumannii

Abstract Acinetobacter baumannii, an opportunistic bacterium prevalent in various environment, is a significant cause of nosocomial infections in ICUs. As the causative agent of pneumonia, septicemia, and meningitis, A. baumannii typically exhibits multidrug resistance and is associated with poor pr...

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Bibliographic Details
Main Authors: Shiyang Ma, Fei Zhu, Peipei Zhang, Yizhong Xu, Ziyou Zhou, Hang Yang, Caixia Tan, Jie Chen, Pinhua Pan
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Acinetobacter baumannii
Multiepitope vaccine
Molecular docking
Molecular dynamics
mRNA vaccine
Online Access:https://doi.org/10.1038/s41598-024-84823-0
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