‘Making Moves’: Protocol for a hybrid effectiveness-implementation pre-post trial of a co-designed online physical activity program for childhood cancer survivors
Background: Childhood cancer survivors are at increased risk of developing chronic health conditions, including cardiovascular disease. Cardiovascular disease risk is further exacerbated by low physical activity levels and high levels of sedentary behaviour. Yet many survivors do not meet the physic...
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Elsevier
2025-06-01
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| Series: | JSAMS Plus |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772696725000134 |
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| author | Lauren Ha Claire E. Wakefield Jacqueline Jacovou Karen Johnston Donna Drew Mark W. Donoghoe David Mizrahi Richard De Abreu Lourenco Richard J. Cohn Natalie Taylor Christina Signorelli Kiarn Roughley Callum Joyner Aj Wright |
| author_facet | Lauren Ha Claire E. Wakefield Jacqueline Jacovou Karen Johnston Donna Drew Mark W. Donoghoe David Mizrahi Richard De Abreu Lourenco Richard J. Cohn Natalie Taylor Christina Signorelli Kiarn Roughley Callum Joyner Aj Wright |
| author_sort | Lauren Ha |
| collection | DOAJ |
| description | Background: Childhood cancer survivors are at increased risk of developing chronic health conditions, including cardiovascular disease. Cardiovascular disease risk is further exacerbated by low physical activity levels and high levels of sedentary behaviour. Yet many survivors do not meet the physical activity guidelines, and those living in regional and remote areas have limited access to exercise interventions and cancer care programs. Therefore, it is critical that physical activity programs are accessible for childhood cancer survivors, no matter where they live. This protocol describes the development and planned evaluation of ‘Making Moves’, a co-designed online physical activity program for childhood cancer survivors aged 8–21 years. Methods and analysis: This type I hybrid effectiveness-implementation pre-post trial will simultaneously (i) test the potential effectiveness of Making Moves on survivors' physical activity self-efficacy, and (ii) explore barriers and facilitators to implementation from multiple levels (individual, provider, organisational, and community) to inform future adaptations and implementation strategies. Making Moves includes an 8-week online program offering eight age-appropriate health behaviour educational modules with guided home-based physical activity videos, and up to five tailored telehealth sessions with an Accredited Exercise Physiologist. Assessment of the primary outcome (physical activity self-efficacy, i.e., perceived ability to engage in physical activity) and secondary outcomes (physical activity levels, aerobic fitness, muscular strength, symptoms of depression, readiness to exercise, perceived enjoyment of exercise, health-related quality of life) will occur at baseline (week 0), post-intervention (week 9), and follow-up (6 months). To assess the factors affecting the program’s implementation, we will conduct a process evaluation guided by the Consolidated Framework for Implementation Research 2.0 to interview survivors and parents, and future potential implementors. To judge the potential implementation success of Making Moves, we will collect implementation data (feasibility, acceptability, costs) for our process evaluation throughout the trial. Ethics and dissemination: Ethical approval was obtained from the Sydney Children’s Hospital Network Human Research Ethics Committee (2023/ETH01614). We will publish our findings in peer-reviewed journals, present findings at relevant medical and scientific conferences, and disseminate research updates via newsletters to stakeholders and community networks. Trial registration number: ANZCTR12623000188639. Registered 22 Feb 2023. |
| format | Article |
| id | doaj-art-dda183eee9f44bb6aac53f6a4f0c4c88 |
| institution | Kabale University |
| issn | 2772-6967 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | JSAMS Plus |
| spelling | doaj-art-dda183eee9f44bb6aac53f6a4f0c4c882025-08-20T03:45:11ZengElsevierJSAMS Plus2772-69672025-06-01510009910.1016/j.jsampl.2025.100099‘Making Moves’: Protocol for a hybrid effectiveness-implementation pre-post trial of a co-designed online physical activity program for childhood cancer survivorsLauren Ha0Claire E. Wakefield1Jacqueline Jacovou2Karen Johnston3Donna Drew4Mark W. Donoghoe5David Mizrahi6Richard De Abreu Lourenco7Richard J. Cohn8Natalie Taylor9Christina Signorelli10Kiarn RoughleyCallum JoynerAj WrightBehavioural Sciences Unit, Discipline of Paediatrics & Child Health, School of Clinical Medicine, Randwick Clinical Campus, UNSW Medicine & Health, UNSW SYDNEY, Australia; Kids Cancer Centre, Sydney Children’s Hospital, Randwick, NSW, Australia; Corresponding author. Behavioural Sciences Unit, Kids Cancer Centre, Sydney Children’s Hospital, Randwick, NSW, 2031, Australia.Behavioural Sciences Unit, Discipline of Paediatrics & Child Health, School of Clinical Medicine, Randwick Clinical Campus, UNSW Medicine & Health, UNSW SYDNEY, Australia; Kids Cancer Centre, Sydney Children’s Hospital, Randwick, NSW, AustraliaBehavioural Sciences Unit, Discipline of Paediatrics & Child Health, School of Clinical Medicine, Randwick Clinical Campus, UNSW Medicine & Health, UNSW SYDNEY, Australia; Kids Cancer Centre, Sydney Children’s Hospital, Randwick, NSW, AustraliaKids Cancer Centre, Sydney Children’s Hospital, Randwick, NSW, AustraliaKids Cancer Centre, Sydney Children’s Hospital, Randwick, NSW, AustraliaClinical Research Unit, UNSW Medicine & Health, UNSW, Sydney, AustraliaThe Daffodil Centre, The University of Sydney, a Joint Venture with Cancer Council NSW, AustraliaCentre for Health Economics Research and Evaluation, UTS, Sydney, AustraliaBehavioural Sciences Unit, Discipline of Paediatrics & Child Health, School of Clinical Medicine, Randwick Clinical Campus, UNSW Medicine & Health, UNSW SYDNEY, Australia; Kids Cancer Centre, Sydney Children’s Hospital, Randwick, NSW, AustraliaSchool of Population Health, UNSW Medicine & Health, UNSW, Sydney, AustraliaBehavioural Sciences Unit, Discipline of Paediatrics & Child Health, School of Clinical Medicine, Randwick Clinical Campus, UNSW Medicine & Health, UNSW SYDNEY, Australia; Kids Cancer Centre, Sydney Children’s Hospital, Randwick, NSW, AustraliaBackground: Childhood cancer survivors are at increased risk of developing chronic health conditions, including cardiovascular disease. Cardiovascular disease risk is further exacerbated by low physical activity levels and high levels of sedentary behaviour. Yet many survivors do not meet the physical activity guidelines, and those living in regional and remote areas have limited access to exercise interventions and cancer care programs. Therefore, it is critical that physical activity programs are accessible for childhood cancer survivors, no matter where they live. This protocol describes the development and planned evaluation of ‘Making Moves’, a co-designed online physical activity program for childhood cancer survivors aged 8–21 years. Methods and analysis: This type I hybrid effectiveness-implementation pre-post trial will simultaneously (i) test the potential effectiveness of Making Moves on survivors' physical activity self-efficacy, and (ii) explore barriers and facilitators to implementation from multiple levels (individual, provider, organisational, and community) to inform future adaptations and implementation strategies. Making Moves includes an 8-week online program offering eight age-appropriate health behaviour educational modules with guided home-based physical activity videos, and up to five tailored telehealth sessions with an Accredited Exercise Physiologist. Assessment of the primary outcome (physical activity self-efficacy, i.e., perceived ability to engage in physical activity) and secondary outcomes (physical activity levels, aerobic fitness, muscular strength, symptoms of depression, readiness to exercise, perceived enjoyment of exercise, health-related quality of life) will occur at baseline (week 0), post-intervention (week 9), and follow-up (6 months). To assess the factors affecting the program’s implementation, we will conduct a process evaluation guided by the Consolidated Framework for Implementation Research 2.0 to interview survivors and parents, and future potential implementors. To judge the potential implementation success of Making Moves, we will collect implementation data (feasibility, acceptability, costs) for our process evaluation throughout the trial. Ethics and dissemination: Ethical approval was obtained from the Sydney Children’s Hospital Network Human Research Ethics Committee (2023/ETH01614). We will publish our findings in peer-reviewed journals, present findings at relevant medical and scientific conferences, and disseminate research updates via newsletters to stakeholders and community networks. Trial registration number: ANZCTR12623000188639. Registered 22 Feb 2023.http://www.sciencedirect.com/science/article/pii/S2772696725000134Childhood cancerSurvivorshipPhysical activityExerciseDigital healthImplementation |
| spellingShingle | Lauren Ha Claire E. Wakefield Jacqueline Jacovou Karen Johnston Donna Drew Mark W. Donoghoe David Mizrahi Richard De Abreu Lourenco Richard J. Cohn Natalie Taylor Christina Signorelli Kiarn Roughley Callum Joyner Aj Wright ‘Making Moves’: Protocol for a hybrid effectiveness-implementation pre-post trial of a co-designed online physical activity program for childhood cancer survivors JSAMS Plus Childhood cancer Survivorship Physical activity Exercise Digital health Implementation |
| title | ‘Making Moves’: Protocol for a hybrid effectiveness-implementation pre-post trial of a co-designed online physical activity program for childhood cancer survivors |
| title_full | ‘Making Moves’: Protocol for a hybrid effectiveness-implementation pre-post trial of a co-designed online physical activity program for childhood cancer survivors |
| title_fullStr | ‘Making Moves’: Protocol for a hybrid effectiveness-implementation pre-post trial of a co-designed online physical activity program for childhood cancer survivors |
| title_full_unstemmed | ‘Making Moves’: Protocol for a hybrid effectiveness-implementation pre-post trial of a co-designed online physical activity program for childhood cancer survivors |
| title_short | ‘Making Moves’: Protocol for a hybrid effectiveness-implementation pre-post trial of a co-designed online physical activity program for childhood cancer survivors |
| title_sort | making moves protocol for a hybrid effectiveness implementation pre post trial of a co designed online physical activity program for childhood cancer survivors |
| topic | Childhood cancer Survivorship Physical activity Exercise Digital health Implementation |
| url | http://www.sciencedirect.com/science/article/pii/S2772696725000134 |
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