Multiparameter flow cytometry enables immune profiling and IFN pathway analysis in human minor salivary glands

Multiparameter flow cytometry enables immune profiling and IFN pathway analysis in human minor salivary glands

Aim/IntroductionWe aimed to achieve direct quantitative measurement of activated and therapeutically actionable pathways (e.g., Type-I interferon) in target organs of autoimmune disease using flow cytometry of human salivary glands. Sjögren's Disease (SjD) is a systemic autoimmune disorder char...

Full description

Saved in:

Bibliographic Details
Main Authors:	Eiko Yamada, Kalie Dominick, Rachel J. Kulchar, Joseph Twohig, Zohreh Khavandgar, Margaret Beach, Eileen Pelayo, Alan Baer, Paola Perez, Blake M. Warner
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-06-01
Series:	Frontiers in Dental Medicine
Subjects:	salivary glands Sjogren's disease tissue dissociation IFN pathway cytometry flow cytometry
Online Access:	https://www.frontiersin.org/articles/10.3389/fdmed.2025.1590516/full
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

The Power of Reagent Titration in Flow Cytometry
by: Diana L. Bonilla, et al.
Published: (2024-10-01)

Neuromorphic imaging cytometry on human blood cells
by: Ziyao Zhang, et al.
Published: (2025-01-01)

Diverse Lenabasum pathway activation in dermatomyositis patients’ blood
by: Nilesh Kodali, et al.
Published: (2025-05-01)

Protocol for quantification of circulating immature granulocytes in patients with a chronic myeloid malignancy using flow cytometry
by: Margot Morabito, et al.
Published: (2025-09-01)

Use of 2-color flow cytometry to assess radiation-induced genotoxic damage on CHO-KI cells
by: Luma Ramirez de Carvalho, et al.
Published: (2019-02-01)

Study of myelodysplastic features in patients with myelodysplastic syndromes by multicolor flow cytometry
by: O. Yu. Davydova, et al.
Published: (2019-01-01)

DIAGNOSTIC UTILITY OF FLOW CYTOMETRY IN MYELODYSPLASTIC SYNDROMES.
by: Matteo Della Porta, et al.
Published: (2017-02-01)

The role of RNA structural motifs in RNA-lipid raft interaction
by: Rafał Mańka, et al.
Published: (2025-02-01)

Beyond the Limits: How Is Spectral Flow Cytometry Reshaping the Clinical Landscape and What Is Coming Next?
by: Kamila Czechowska, et al.
Published: (2025-06-01)

Evaluation of real-time PCR and flow cytometry efficiency in rapid detection of carbapenemase-producing Enterobacteriales
by: İpek Koçer, et al.
Published: (2023-05-01)

Protocol for phenotyping mouse myeloid and lymphoid cells by mass cytometry
by: Laura Morin, et al.
Published: (2025-03-01)

Nano‐Flow Cytometry‐Guided Discrimination and Separation of Human Cytomegalovirus Virions and Extracellular Vesicles
by: Vladimir Bokun, et al.
Published: (2025-05-01)

Modern methods for studying atherosclerosis and coronary artery disease: flow cytometry
by: E. M. Stakhneva, et al.
Published: (2021-07-01)

Protocol for Agrobacterium-mediated transformation of tomato and flow cytometry-based ploidy confirmation
by: Yiming Wang, et al.
Published: (2025-09-01)

Determination of osmotic resistance of erythrocytes using flow cytometry in patients with hereditary spherocytosis
by: E. F. Mitsura, et al.
Published: (2020-07-01)

MULTICOLOR FLOW CYTOMETRY AS A DIAGNOSTIC TOOL IN MYELODYSPLASTIC SYNDROMES
by: Yu. O. Davydova, et al.
Published: (2018-05-01)

Determination of total bacterial count in raw milk by flow cytometry
by: Dubravka Samaržija, et al.
Published: (2004-01-01)

Imaging Flow Cytometry in HIV Infection Research: Advantages and Opportunities
by: Kirill. A. Elfimov, et al.
Published: (2025-02-01)

Microplastics and nanoplastics detection using flow cytometry: Challenges and methodological advances with fluorescent dye application
by: Lucas Ainé, et al.
Published: (2025-06-01)

Study of body fluid samples using flow cytometry: Six years of experience at the Hospital Universitario San Ignacio - Pontificia Universidad Javeriana Bogota - Colombia
by: Alba, et al.
Published: (2017-05-01)

IMMUNOLOGICAL REACTIVITY AND PERIPHERAL BLOOD DNA-CYTOMETRY IN CHILDHOOD ONCOLOGICAL DISEASES
by: Z. R. Khamatdinova, et al.
Published: (2014-07-01)

Flow Cytometry Method as a Diagnostic Tool for Pleural Fluid Involvement in a Patient with Multiple Myeloma
by: Muzaffer Keklik, et al.
Published: (2012-10-01)

MuPETFlow: multiple ploidy estimation tool from flow cytometry data
by: C. Gómez-Muñoz, et al.
Published: (2025-03-01)

FLOW CYTOMETRY BASED MICRONUCLEUS ASSAY FOR EVALUATION OF GENOTOXIC POTENTIAL OF 2-ACBs IN HEPATIC CELLS HepG2
by: Angélica Bueno Barbezan
Published: (2019-02-01)

EXPANSION OF OPPORTUNITIES OF THE FLOW CYTOMETRY METHOD FOR CLINICAL AND IMMUNOLOGYCAL PRACTICE
by: S. V. Khaidukov, et al.
Published: (2014-07-01)

Clinical possibilities of flow cytometry in hodgkin’s lymphoma
by: F. M. Abbasbeyli, et al.
Published: (2023-09-01)

FLOW CYTOMETRY IN THE DIAGNOSIS AND MONITORING OF MINIMAL RESIDUAL DISEASE IN MULTIPLE MYELOMA
by: I. V. Galtseva, et al.
Published: (2017-06-01)

Refining Flow Cytometry-based Sorting of Plasma-derived Extracellular Vesicles
by: Daniele Reverberi, et al.
Published: (2025-08-01)

Femtosecond laser microfabrication of a fully-integrated optofluidic device for 3D imaging flow cytometry
by: Federico Sala, et al.
Published: (2025-04-01)

Application of Flow Cytometry to Determine Cell DNA Content in the Genetic Breeding of Fish
by: Xinyan Zhu, et al.
Published: (2025-05-01)

Estimation of bacterio‐, picophyto‐ and nanophytoplankton abundance in the Middle Caspian Sea by flow cytometry
by: V. S. Mukhanov, et al.
Published: (2024-10-01)

Features of B cell subsets in primary Sjogren’s syndrome and systemic lupus erythematosus
by: S. S. Benevolenskaya, et al.
Published: (2024-11-01)

STUDY OF MINIMAL RESIDUAL DISEASE BY MULTICOLOR FLOW CYTOMETRY IN MULTIPLE MYELOMA AFTER AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION
by: I. V. Galtseva, et al.
Published: (2017-06-01)

Flow cytometry for evaluating platelet immunophenotyping and function in patients with thrombocytopenia
by: Chih-Lung Shen, et al.
Published: (2022-01-01)

A new method for flow cytometry-based detection of ABO antigen expression levels
by: ZHANG Yuyu, et al.
Published: (2025-05-01)

The utility of flow cytometry for the detection of tumor cells in cerebrospinal fluid of patients with acute leukemia
by: Ximena Torres, et al.
Published: (2022-03-01)

Ultrasound examination of the salivary glands in Sjogren’s disease
by: A. V. Torgashina
Published: (2021-09-01)

Immunomodulation by 4-Hydroxy-TEMPO (TEMPOL) and Dimethyl Fumarate (DMF) After Ventral Root Crush (VRC) in C57BL/6J Mice: A Flow Cytometry Analysis
by: Maria Fernanda Vannucci Balzani, et al.
Published: (2025-04-01)

Evaluation of clopidogrel impact on canine platelet function using flow cytometry and thromboelastography platelet mapping
by: Eunchae Yoon, et al.
Published: (2025-06-01)

Natural regulatory T cells increase significantly in pediatric patients with parasitic infections: Flow cytometry study
by: Nadeem Kizilbash, et al.
Published: (2023-07-01)