Construction of nanodelivery system based on the interaction mechanism between ultrasound–treated soybean whey protein and quercetin: structure, physicochemical stability and bioaccessibility
In this study, soybean whey protein (SWP) nanodelivery system was constructed through ultrasound treatment and quercetin (Que) modification. The effect of ultrasound power on the interaction mode between SWP and Que, and the formation and stability of SWP–Que nanodelivery system were investigated. O...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-01-01
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| Series: | Ultrasonics Sonochemistry |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1350417724004449 |
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| author | Xinru Cao Jia Cao Tianhe Xu Lexi Zheng Jingyi Dai Xiaokun Zhang Tian Tian Kunyu Ren Xiaohong Tong Huan Wang Lianzhou Jiang |
| author_facet | Xinru Cao Jia Cao Tianhe Xu Lexi Zheng Jingyi Dai Xiaokun Zhang Tian Tian Kunyu Ren Xiaohong Tong Huan Wang Lianzhou Jiang |
| author_sort | Xinru Cao |
| collection | DOAJ |
| description | In this study, soybean whey protein (SWP) nanodelivery system was constructed through ultrasound treatment and quercetin (Que) modification. The effect of ultrasound power on the interaction mode between SWP and Que, and the formation and stability of SWP–Que nanodelivery system were investigated. Optimal ultrasound treatment (300–500 W) produced SWP–Que nanoparticles with smaller particle size, higher ζ–potential values, and more uniform dispersion. Fluorescence spectroscopy and FTIR analyses revealed that SWP primarily binds to Que through hydrophobic interactions. Ultrasound treatment induced the unfolding of the SWP structure, thereby increasing its binding affinity to Que. After 400 W sonication, the encapsulation efficiency can reach 95.63 ± 0.60 %. The SWP–Que nanoparticles protected Que from degradation under environmental stresses (heat, UV, and storage) and improved its bioaccessibility during digestion as the ultrasonic power of 400 W. This study highlights the potential of ultrasound–modified SWP nanoparticles for effective nutrient delivery. |
| format | Article |
| id | doaj-art-dd843f13420a41168f49203f46a01e6a |
| institution | Kabale University |
| issn | 1350-4177 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Ultrasonics Sonochemistry |
| spelling | doaj-art-dd843f13420a41168f49203f46a01e6a2025-01-11T06:38:48ZengElsevierUltrasonics Sonochemistry1350-41772025-01-01112107195Construction of nanodelivery system based on the interaction mechanism between ultrasound–treated soybean whey protein and quercetin: structure, physicochemical stability and bioaccessibilityXinru Cao0Jia Cao1Tianhe Xu2Lexi Zheng3Jingyi Dai4Xiaokun Zhang5Tian Tian6Kunyu Ren7Xiaohong Tong8Huan Wang9Lianzhou Jiang10College of Food Science, Northeast Agricultural University, Harbin 150030, ChinaCollege of Food Science, Northeast Agricultural University, Harbin 150030, ChinaCollege of Food Science, Northeast Agricultural University, Harbin 150030, ChinaCollege of Food Science, Northeast Agricultural University, Harbin 150030, ChinaCollege of Food Science, Northeast Agricultural University, Harbin 150030, ChinaCollege of Food Science, Northeast Agricultural University, Harbin 150030, ChinaSchool of Food Science and Engineering, Hainan University, Haikou 570228, ChinaCollege of Food Science, Northeast Agricultural University, Harbin 150030, ChinaCollege of Agricultural, Northeast Agricultural University, Harbin 150030, China; Corresponding authors.College of Food Science, Northeast Agricultural University, Harbin 150030, China; Corresponding authors.College of Food Science, Northeast Agricultural University, Harbin 150030, ChinaIn this study, soybean whey protein (SWP) nanodelivery system was constructed through ultrasound treatment and quercetin (Que) modification. The effect of ultrasound power on the interaction mode between SWP and Que, and the formation and stability of SWP–Que nanodelivery system were investigated. Optimal ultrasound treatment (300–500 W) produced SWP–Que nanoparticles with smaller particle size, higher ζ–potential values, and more uniform dispersion. Fluorescence spectroscopy and FTIR analyses revealed that SWP primarily binds to Que through hydrophobic interactions. Ultrasound treatment induced the unfolding of the SWP structure, thereby increasing its binding affinity to Que. After 400 W sonication, the encapsulation efficiency can reach 95.63 ± 0.60 %. The SWP–Que nanoparticles protected Que from degradation under environmental stresses (heat, UV, and storage) and improved its bioaccessibility during digestion as the ultrasonic power of 400 W. This study highlights the potential of ultrasound–modified SWP nanoparticles for effective nutrient delivery.http://www.sciencedirect.com/science/article/pii/S1350417724004449Soybean whey proteinQuercetinUltrasoundNanoparticlesStructure |
| spellingShingle | Xinru Cao Jia Cao Tianhe Xu Lexi Zheng Jingyi Dai Xiaokun Zhang Tian Tian Kunyu Ren Xiaohong Tong Huan Wang Lianzhou Jiang Construction of nanodelivery system based on the interaction mechanism between ultrasound–treated soybean whey protein and quercetin: structure, physicochemical stability and bioaccessibility Ultrasonics Sonochemistry Soybean whey protein Quercetin Ultrasound Nanoparticles Structure |
| title | Construction of nanodelivery system based on the interaction mechanism between ultrasound–treated soybean whey protein and quercetin: structure, physicochemical stability and bioaccessibility |
| title_full | Construction of nanodelivery system based on the interaction mechanism between ultrasound–treated soybean whey protein and quercetin: structure, physicochemical stability and bioaccessibility |
| title_fullStr | Construction of nanodelivery system based on the interaction mechanism between ultrasound–treated soybean whey protein and quercetin: structure, physicochemical stability and bioaccessibility |
| title_full_unstemmed | Construction of nanodelivery system based on the interaction mechanism between ultrasound–treated soybean whey protein and quercetin: structure, physicochemical stability and bioaccessibility |
| title_short | Construction of nanodelivery system based on the interaction mechanism between ultrasound–treated soybean whey protein and quercetin: structure, physicochemical stability and bioaccessibility |
| title_sort | construction of nanodelivery system based on the interaction mechanism between ultrasound treated soybean whey protein and quercetin structure physicochemical stability and bioaccessibility |
| topic | Soybean whey protein Quercetin Ultrasound Nanoparticles Structure |
| url | http://www.sciencedirect.com/science/article/pii/S1350417724004449 |
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