Dual RNA-seq study of the dynamics of coding and non-coding RNA expression during Clostridioides difficile infection in a mouse model

Dual RNA-seq study of the dynamics of coding and non-coding RNA expression during Clostridioides difficile infection in a mouse model

ABSTRACT Clostridioides difficile is the leading cause of healthcare-associated diarrhea in industrialized countries. Many questions remain to be answered about the mechanisms governing its interaction with the host during infection. Non-coding RNAs (ncRNAs) contribute to shape virulence in many pat...

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Main Authors: Victor Kreis, Claire Toffano-Nioche, Cécile Denève-Larrazet, Jean-Christophe Marvaud, Julian R. Garneau, Florent Dumont, Erwin L. van Dijk, Yan Jaszczyszyn, Anaïs Boutserin, Francesca D'Angelo, Daniel Gautheret, Imad Kansau, Claire Janoir, Olga Soutourina
Format: Article
Language:English
Published: American Society for Microbiology 2024-12-01
Series:mSystems
Subjects:
dual RNA-seq
Clostridioides difficile
host-pathogen interactions
non-coding RNA
gut microbiota
Online Access:https://journals.asm.org/doi/10.1128/msystems.00863-24
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