Diagnosis and management of benign secreting pancreatic insulinoma: What’s new? 4 case report

Introduction and importance: Even though insulinoma is the most frequent neuroendocrine tumor, it represents only 2% of pancreatic 2% of all pancreatic neoplasms. Diagnosis is relatively simple, and surgery after accurate determination of the tumors location within the pancreas is the cornerstone of...

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Main Authors: Khawla Bahou, Youssef Achour, Mehdi Ilahiane, Hamza Sekkat, Younes Bakali, Mouna Mhamdi Alaoui, Mohammed Raiss, Farid Sabbah, Abdelmalek Hrora
Format: Article
Language:English
Published: SAGE Publishing 2025-01-01
Series:Rare Tumors
Online Access:https://doi.org/10.1177/20363613241313409
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author Khawla Bahou
Youssef Achour
Mehdi Ilahiane
Hamza Sekkat
Younes Bakali
Mouna Mhamdi Alaoui
Mohammed Raiss
Farid Sabbah
Abdelmalek Hrora
author_facet Khawla Bahou
Youssef Achour
Mehdi Ilahiane
Hamza Sekkat
Younes Bakali
Mouna Mhamdi Alaoui
Mohammed Raiss
Farid Sabbah
Abdelmalek Hrora
author_sort Khawla Bahou
collection DOAJ
description Introduction and importance: Even though insulinoma is the most frequent neuroendocrine tumor, it represents only 2% of pancreatic 2% of all pancreatic neoplasms. Diagnosis is relatively simple, and surgery after accurate determination of the tumors location within the pancreas is the cornerstone of its treatment. Case presentation: We herein report 4 patients undergoing various surgeries for benign secreting insulinomas, after extensive radiological and endoscopic exploration. Clinical discussion: Diagnosis is relatively simple relying on clinical and biological criteria, it must be followed by an extensive and accurate preoperative determination of the tumors localization. The laparoscopic tumoral enucleation is the treatment of choice for small isolated tumors, but open surgery still has its indications. Conclusion: Pancreatic insulinoma is a rare neuroendocrine tumor that can be life-threatening due to hypoglycemic manifestations. The diagnosis is based on clinical and biological criteria. echo endoscopy and to a lesser extent radiological exploration can precisely determine the tumors location. Laparoscopic surgical enucleation of the tumor remains the preferred curative treatment.
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institution Kabale University
issn 2036-3613
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publisher SAGE Publishing
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series Rare Tumors
spelling doaj-art-dd8363b2bd904981a8078d3dea53d90b2025-01-08T21:03:22ZengSAGE PublishingRare Tumors2036-36132025-01-011710.1177/20363613241313409Diagnosis and management of benign secreting pancreatic insulinoma: What’s new? 4 case reportKhawla BahouYoussef AchourMehdi IlahianeHamza SekkatYounes BakaliMouna Mhamdi AlaouiMohammed RaissFarid SabbahAbdelmalek HroraIntroduction and importance: Even though insulinoma is the most frequent neuroendocrine tumor, it represents only 2% of pancreatic 2% of all pancreatic neoplasms. Diagnosis is relatively simple, and surgery after accurate determination of the tumors location within the pancreas is the cornerstone of its treatment. Case presentation: We herein report 4 patients undergoing various surgeries for benign secreting insulinomas, after extensive radiological and endoscopic exploration. Clinical discussion: Diagnosis is relatively simple relying on clinical and biological criteria, it must be followed by an extensive and accurate preoperative determination of the tumors localization. The laparoscopic tumoral enucleation is the treatment of choice for small isolated tumors, but open surgery still has its indications. Conclusion: Pancreatic insulinoma is a rare neuroendocrine tumor that can be life-threatening due to hypoglycemic manifestations. The diagnosis is based on clinical and biological criteria. echo endoscopy and to a lesser extent radiological exploration can precisely determine the tumors location. Laparoscopic surgical enucleation of the tumor remains the preferred curative treatment.https://doi.org/10.1177/20363613241313409
spellingShingle Khawla Bahou
Youssef Achour
Mehdi Ilahiane
Hamza Sekkat
Younes Bakali
Mouna Mhamdi Alaoui
Mohammed Raiss
Farid Sabbah
Abdelmalek Hrora
Diagnosis and management of benign secreting pancreatic insulinoma: What’s new? 4 case report
Rare Tumors
title Diagnosis and management of benign secreting pancreatic insulinoma: What’s new? 4 case report
title_full Diagnosis and management of benign secreting pancreatic insulinoma: What’s new? 4 case report
title_fullStr Diagnosis and management of benign secreting pancreatic insulinoma: What’s new? 4 case report
title_full_unstemmed Diagnosis and management of benign secreting pancreatic insulinoma: What’s new? 4 case report
title_short Diagnosis and management of benign secreting pancreatic insulinoma: What’s new? 4 case report
title_sort diagnosis and management of benign secreting pancreatic insulinoma what s new 4 case report
url https://doi.org/10.1177/20363613241313409
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