A comparative analysis of drug-induced kidney injury adverse reactions between cyclosporine and tacrolimus based on the FAERS database

A comparative analysis of drug-induced kidney injury adverse reactions between cyclosporine and tacrolimus based on the FAERS database

Abstract Background This study utilizes the FDA Adverse Event Reporting System (FAERS) database to compare the adverse reaction signals of cyclosporine and tacrolimus, two widely used immunosuppressants, in relation to drug-induced kidney injury. The findings aim to inform clinical decision-making....

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Bibliographic Details
Main Authors: Min Xu, Shanggang Xu, Xueliang Yi
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Immunology
Subjects:
Cyclosporine
Tacrolimus
Kidney injury
Adverse drug events
FDA adverse event reporting system
Real-world analysis
Online Access:https://doi.org/10.1186/s12865-025-00714-7
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