The Hypoxia‐Associated High‐Risk Cell Subpopulation Distinctly Enhances the Progression of Glioma

The Hypoxia‐Associated High‐Risk Cell Subpopulation Distinctly Enhances the Progression of Glioma

Abstract Less‐aggressive lower‐grade gliomas (LGGs) frequently transform into glioblastoma (GBM). Most previous studies of gliomas have not focused on LGG‐original high‐risk subpopulations, which may be one of the most critical hallmarks of glioma progression. In this study, LGG samples are collecte...

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Main Authors: Quan Wan, Xuechao Wu, Jinxu Zhou, Weiqi Wu, Yuanliang Cao, Cuiping Sun, Zheng Li, Zhicheng Gong, Hong Tang, Qilin Li, Junsheng Chu, Qing Wang, Kaisa Cui, Xiaojie Lu
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Advanced Science
Subjects:
glioblastoma
hypoxia
lower‐grade glioma
organoid
single‐cell sequencing
Online Access:https://doi.org/10.1002/advs.202416231
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