KIF2C Deletion Causes Meiotic Abnormalities and Nonobstructive Azoospermia in Mice

KIF2C Deletion Causes Meiotic Abnormalities and Nonobstructive Azoospermia in Mice

ABSTRACT Purpose Kinesin Family Member 2C (KIF2C) is a key regulator of microtubule dynamics and chromosome segregation in mitosis. However, its role in spermatogenesis remains unclear. Recent transcriptomic analyses suggest a potential link between KIF2C and male infertility. This study aimed to cl...

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Main Authors: Hiroaki Kitakaze, Haruhiko Miyata, Yuki Oyama, Chen Pan, Yuma Kujime, Go Tsujimura, Takahiro Imanaka, Sohei Kuribayashi, Norichika Ueda, Kentaro Takezawa, Shinichiro Fukuhara, Norio Nonomura, Masahito Ikawa
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Reproductive Medicine and Biology
Subjects:
KIF2C
knockout mice
male infertility
nonobstructive azoospermia
Online Access:https://doi.org/10.1002/rmb2.12659
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https://doi.org/10.1002/rmb2.12659

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