Dementia incidence among a cohort of lebanese older adults: first incidence estimates from the Middle East and North Africa region
ObjectiveTo provide the first estimates of dementia incidence rates among elderly in Lebanon.MethodsThe cohort established in 2013 consisted of 470 elderly from Beirut and Mount Lebanon, who consented to be followed-up. In 2017, we reached 341 participants/informants, achieving a response rate of 72...
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Dementia |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/frdem.2024.1494719/full |
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| author | Monique Chaaya Sarah Assaad Hala Darwish Marc Haber Rosemary Khoury Dahlia Saab Khalil El Asmar Ramzi Hajjar |
| author_facet | Monique Chaaya Sarah Assaad Hala Darwish Marc Haber Rosemary Khoury Dahlia Saab Khalil El Asmar Ramzi Hajjar |
| author_sort | Monique Chaaya |
| collection | DOAJ |
| description | ObjectiveTo provide the first estimates of dementia incidence rates among elderly in Lebanon.MethodsThe cohort established in 2013 consisted of 470 elderly from Beirut and Mount Lebanon, who consented to be followed-up. In 2017, we reached 341 participants/informants, achieving a response rate of 72.6%. The validated Arabic version of the 10/66 Dementia Research Group diagnostic tool was administered through face-to-face interviews. Direct age standardization was applied to the data using the Western European population distribution. Age-, sex- and location-specific incidence rates were estimated.ResultsAfter 3.5 years of follow up, 19 new cases of dementia were identified among 229 surviving participants. The crude incidence rate was 16.8 per 1,000 p-y, and the age standardized rate was 20.5 per 1,000 p-y. The incidence rate increased with age, going from 6.5 for those aged 65–74 years to 54.0 for those aged 85–89 years. Incidence rate was higher among females than males (20.7 vs.12.0), and higher in Mount Lebanon, as compared to the capital city Beirut (19.5 vs.14.9).ConclusionDementia incidence rate was close to European and North American countries' estimates. The use of validated tools increased the internal validity of our results. A large cohort study is warranted to confirm these results. |
| format | Article |
| id | doaj-art-dd027e5d5e9c438f8a450fca1e0e0466 |
| institution | Kabale University |
| issn | 2813-3919 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Dementia |
| spelling | doaj-art-dd027e5d5e9c438f8a450fca1e0e04662025-01-07T04:13:40ZengFrontiers Media S.A.Frontiers in Dementia2813-39192025-01-01310.3389/frdem.2024.14947191494719Dementia incidence among a cohort of lebanese older adults: first incidence estimates from the Middle East and North Africa regionMonique Chaaya0Sarah Assaad1Hala Darwish2Marc Haber3Rosemary Khoury4Dahlia Saab5Khalil El Asmar6Ramzi Hajjar7Department of Epidemiology and Population Health, American University of Beirut, Beirut, LebanonResearch Department of Epidemiology and Public Health, University College London, London, United KingdomDepartment of Neurology, University of Michigan School of Nursing, Ann Arbor, MI, United StatesDepartment of Epidemiology and Population Health, American University of Beirut, Beirut, LebanonDivision of Neurosurgery, American University of Beirut, Beirut, LebanonDepartment of Epidemiology and Population Health, American University of Beirut, Beirut, LebanonDepartment of Epidemiology and Population Health, American University of Beirut, Beirut, LebanonDepartment of Internal Medicine, American University of Beirut Medical Center, Beirut, LebanonObjectiveTo provide the first estimates of dementia incidence rates among elderly in Lebanon.MethodsThe cohort established in 2013 consisted of 470 elderly from Beirut and Mount Lebanon, who consented to be followed-up. In 2017, we reached 341 participants/informants, achieving a response rate of 72.6%. The validated Arabic version of the 10/66 Dementia Research Group diagnostic tool was administered through face-to-face interviews. Direct age standardization was applied to the data using the Western European population distribution. Age-, sex- and location-specific incidence rates were estimated.ResultsAfter 3.5 years of follow up, 19 new cases of dementia were identified among 229 surviving participants. The crude incidence rate was 16.8 per 1,000 p-y, and the age standardized rate was 20.5 per 1,000 p-y. The incidence rate increased with age, going from 6.5 for those aged 65–74 years to 54.0 for those aged 85–89 years. Incidence rate was higher among females than males (20.7 vs.12.0), and higher in Mount Lebanon, as compared to the capital city Beirut (19.5 vs.14.9).ConclusionDementia incidence rate was close to European and North American countries' estimates. The use of validated tools increased the internal validity of our results. A large cohort study is warranted to confirm these results.https://www.frontiersin.org/articles/10.3389/frdem.2024.1494719/fulldementia incidenceAlzheimer's diseaseMENA regionincidence ratesgender differencesregional differences |
| spellingShingle | Monique Chaaya Sarah Assaad Hala Darwish Marc Haber Rosemary Khoury Dahlia Saab Khalil El Asmar Ramzi Hajjar Dementia incidence among a cohort of lebanese older adults: first incidence estimates from the Middle East and North Africa region Frontiers in Dementia dementia incidence Alzheimer's disease MENA region incidence rates gender differences regional differences |
| title | Dementia incidence among a cohort of lebanese older adults: first incidence estimates from the Middle East and North Africa region |
| title_full | Dementia incidence among a cohort of lebanese older adults: first incidence estimates from the Middle East and North Africa region |
| title_fullStr | Dementia incidence among a cohort of lebanese older adults: first incidence estimates from the Middle East and North Africa region |
| title_full_unstemmed | Dementia incidence among a cohort of lebanese older adults: first incidence estimates from the Middle East and North Africa region |
| title_short | Dementia incidence among a cohort of lebanese older adults: first incidence estimates from the Middle East and North Africa region |
| title_sort | dementia incidence among a cohort of lebanese older adults first incidence estimates from the middle east and north africa region |
| topic | dementia incidence Alzheimer's disease MENA region incidence rates gender differences regional differences |
| url | https://www.frontiersin.org/articles/10.3389/frdem.2024.1494719/full |
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