Gating-spring stiffness increases outer-hair-cell bundle stiffness, damping, and receptor current

Gating-spring stiffness increases outer-hair-cell bundle stiffness, damping, and receptor current

Abstract In our ears, outer-hair-cell bundles (OHBs) convert sound-induced forces into receptor currents that drive cochlear amplification, the process responsible for the micropascal-scale threshold and million-fold dynamic range of hearing. OHBs rely on gating springs to open mechanoelectrical-tra...

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Bibliographic Details
Main Authors: Zenghao Zhu, Wisam Reid, Dáibhid Ó Maoiléidigh
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Subjects:
Mechanotransduction
Cell mechanics
Hearing
Balance
Hair bundle
Hair cell
Online Access:https://doi.org/10.1038/s41598-024-81355-5
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