Edonerpic maleate prevents epileptic seizure during recovery from brain damage by balancing excitatory and inhibitory inputs

Edonerpic maleate prevents epileptic seizure during recovery from brain damage by balancing excitatory and inhibitory inputs

Functional recovery from brain damage, such as stroke, is a plastic process in the brain. The excitatory glutamate α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor (AMPAR) plays a crucial role in neuronal functions, and the synaptic trafficking of AMPAR is a fundamental mechanism under...

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Bibliographic Details
Main Authors: Yuki Katsuno, Susumu Jitsuki, Wataru Ota, Tomomi Yamanoue, Hiroki Abe, Takuya Takahashi
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Neural Circuits
Subjects:
AMPA receptors
edonerpic maleate
epileptic seizure
stroke
functional recovery
brain damage
Online Access:https://www.frontiersin.org/articles/10.3389/fncir.2024.1492043/full
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