Assessment of the impact of surgical treatment of primary malignant bone tumors on the quality of life of patients in peacetime and in the realities of wartime in Ukraine
Background. The experience of researchers and clinicians in many clinics around the world shows that primary malignant bone tumors are one of the least studied groups of neoplasms, the diagnosis and treatment of which is a difficult task. The purpose was to assess the impact of surgical treatment of...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Zaslavsky O.Yu.
2024-12-01
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| Series: | Bolʹ, Sustavy, Pozvonočnik |
| Subjects: | |
| Online Access: | https://pjs.zaslavsky.com.ua/index.php/journal/article/view/436 |
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| Summary: | Background. The experience of researchers and clinicians in many clinics around the world shows that primary malignant bone tumors are one of the least studied groups of neoplasms, the diagnosis and treatment of which is a difficult task. The purpose was to assess the impact of surgical treatment of primary malignant bone tumors on the quality of life of patients in peacetime and in the realities of wartime in Ukraine. Materials and methods. Surgical treatment of 76 subjects with primary malignant tumors of the lower extremities (osteosarcoma and chondrosarcoma) was carried out: 32 patients were treated from 2019 to 2021, and 44 patients from 2022 to 2024. Patient’s quality of life index before and 3 weeks after surgical treatment was measured by the simplified version of the QLQ-C30 questionnaire, neurological component was evaluated according to our integrated version of the Hospital Anxiety and Depression Scale (HADS) for hospitalized cancer patients and the Montreal MoCA scale. Results. In the study group, the value of the quality of life index after treatment was 27.0 % higher than the value before treatment. In contrast, in the reference group, which shows data before the start of martial law, the value of the quality of life index increased after treatment by 114.5 %. In the reference group after treatment, the percentage of subjects with occasional anxiety decreased from 69 to 53 %, and with constant anxiety — by 3 times, that is, from 19 to 6 %; in the study group, the indices significantly did not change. The overall number of persons with anxiety remained unchanged at 84 %, while in the reference group, this index decreased from 88 to 59 %. Conclusions. Significantly higher results in improving the quality of life were demonstrated by the reference group — the value of the quality of life index of patients increased by 114.5 % after treatment. Among the neurological symptoms in the study group, anxiety prevails, the frequency of which did not decrease even after the treatment and remained unchanged at the level of 84 %, which also confirms the influence of chronic stress during the war. |
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| ISSN: | 2224-1507 2307-1133 |