Cannabinoid receptor 2 selective agonist ameliorates adjuvant-induced arthritis by modulating the balance between Treg and Th17 cells

Cannabinoid receptor 2 selective agonist ameliorates adjuvant-induced arthritis by modulating the balance between Treg and Th17 cells

BackgroundAdjuvant-induced arthritis (AIA) serves as a classic model for rheumatoid arthritis (RA), typified by inflammatory cell infiltration and joint damage. This study explores the therapeutic efficacy of HU-308, a CB2 receptor-specific agonist, on inflammation and immune balance in AIA.MethodsA...

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Bibliographic Details
Main Authors:	Na Tian, Cui Yang, Yu Du, Miao Chen, Bin Li, Dan Li, Sheng-Ming Dai
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-01-01
Series:	Frontiers in Pharmacology
Subjects:	rheumatoid arthritis cannabinoid receptor 2 Th17/Treg balance adjuvant-induced arthritis cd4+ T cell differentiation
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1532518/full
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