CHI-KAT8i5 suppresses ESCC tumor growth by inhibiting KAT8-mediated c-Myc stability

CHI-KAT8i5 suppresses ESCC tumor growth by inhibiting KAT8-mediated c-Myc stability

Summary: The integrated analysis of histone modifier enzymes in solid tumors, especially in esophageal squamous cell carcinoma (ESCC), is still inadequate. Here, we investigate the expression levels of histone modifier enzymes in ESCC tissues. Notably, KAT8 (lysine acetyltransferase 8) is identified...

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Bibliographic Details
Main Authors: Dandan Zhang, Ming Jiang, Pan Li, Kyle Vaughn Laster, Dengyun Zhao, Yafei Zhi, Huifang Wei, Wenna Nie, Yunfeng Gao, Qiong Wu, Pu Xiang, Xinyu He, Kangdong Liu, Zigang Dong
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Cell Reports
Subjects:
CP: Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724014864
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