The effects of cell displacement on DNA damages in targeted radiation therapy using Geant4-DNA

The effects of cell displacement on DNA damages in targeted radiation therapy using Geant4-DNA

Abstract Charged particle radiation can, directly and indirectly, affect cells by breaking DNA strands. This effect includes DNA single-strand breaks (SSB) and DNA double-strand breaks (DSB), which may cause cell death and mitotic failure. Thus, using short-range charged particles such as Auger elec...

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Bibliographic Details
Main Authors: Ali Azizi Ganjgah, Payvand Taherparvar
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Subjects:
Monte Carlo study
DNA damage
SSB
DSB
HDSB
Auger electron
Online Access:https://doi.org/10.1038/s41598-024-81863-4
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