Glucose metabolism and its direct action in cancer and immune regulation: opportunities and challenges for metabolic targeting

Glucose metabolism and its direct action in cancer and immune regulation: opportunities and challenges for metabolic targeting

Abstract Glucose metabolism is a pivotal hub for cellular energy production and the generation of building blocks that support cell growth, survival, and differentiation. Cancer cells undergo metabolic reprogramming to sustain rapid proliferation, survive in harsh microenvironments, and resist thera...

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Bibliographic Details
Main Authors: Bo-Syong Pan, Che-Chia Hsu, Hsin-En Wu, Yuan-Ru Chen, Xiaobo Zhou, Shu-Chi Wang, Chia-Yang Li, Hui-Kuan Lin
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Journal of Biomedical Science
Subjects:
Glucose metabolism
Warburg effect
Tumor microenvironment
Immune regulation
Glucose sensor
Immunotherapy resistance
Online Access:https://doi.org/10.1186/s12929-025-01167-1
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