Spironolactone Protects against Diabetic Cardiomyopathy in Streptozotocin-Induced Diabetic Rats

Spironolactone Protects against Diabetic Cardiomyopathy in Streptozotocin-Induced Diabetic Rats

Spironolactone (SPR) has been shown to protect diabetic cardiomyopathy (DCM), but the specific mechanisms are not fully understood. Here, we determined the cardioprotective role of SPR in diabetic mice and further explored the potential mechanisms in both in vivo and in vitro models. Streptozotocin-...

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Main Authors: Wenjuan Liu, Wei Gong, Min He, Yemei Liu, Yeping Yang, Meng Wang, Meng Wu, Shizhe Guo, Yifei Yu, Xuanchun Wang, Fei Sun, Yiming Li, Linuo Zhou, Shengmei Qin, Zhaoyun Zhang
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Journal of Diabetes Research
Online Access:http://dx.doi.org/10.1155/2018/9232065
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