Indications, complications and outcomes of minimally-invasive lateral lumbar interbody fusion with anterior column realignment vs. standard LLIF using expandable interbody spacers

BackgroundAnterior column realignment (ACR), using a lateral lumbar or thoracic interbody fusion (LLIF) approach to release the anterior longitudinal ligament (ALL), is a powerful technique to increase segmental lordosis. We here report our experience with the use of expandible LLIF cages for ACR.Me...

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Main Authors: Gregor Fischer, Linda Bättig, Thomas Schöfl, Ethan Schonfeld, Anand Veeravagu, Benjamin Martens, Martin N. Stienen
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Surgery
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Online Access:https://www.frontiersin.org/articles/10.3389/fsurg.2024.1455445/full
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author Gregor Fischer
Gregor Fischer
Linda Bättig
Linda Bättig
Thomas Schöfl
Thomas Schöfl
Ethan Schonfeld
Anand Veeravagu
Benjamin Martens
Benjamin Martens
Martin N. Stienen
Martin N. Stienen
author_facet Gregor Fischer
Gregor Fischer
Linda Bättig
Linda Bättig
Thomas Schöfl
Thomas Schöfl
Ethan Schonfeld
Anand Veeravagu
Benjamin Martens
Benjamin Martens
Martin N. Stienen
Martin N. Stienen
author_sort Gregor Fischer
collection DOAJ
description BackgroundAnterior column realignment (ACR), using a lateral lumbar or thoracic interbody fusion (LLIF) approach to release the anterior longitudinal ligament (ALL), is a powerful technique to increase segmental lordosis. We here report our experience with the use of expandible LLIF cages for ACR.MethodsRetrospective, single-center observational cohort study including consecutive patients treated by LLIF using an expandible interbody implant. Patients with ACR were compared to patients without ACR. Our outcomes include adverse events (AEs), radiological (segmental sagittal cobb angle, spinopelvic parameters) and clinical outcomes until 12 months postoperative.ResultsWe identified 503 patients, in which we performed LLIF at 732 levels. In 63 patients (12.5%) and 70 levels (9.6%) an expandable cage was used. Of those, in 30 patients (47.6%) and 30 levels, the ALL was released (42.8%). Age (mean 61.4 years), sex (57.1% female), comorbidities and further demographic features were similar, but patients in the ACR group had a higher anesthesiologic risk, were more frequently operated for degenerative deformity and had a more severely dysbalanced spine (all p < 0.05). ACR was most frequently done at L3/4 (36.7%) and L4/5 (23.3%), entailing multilevel fusions in 50% (3–7 levels) and long constructs in 26.7% (>7 levels). Intraoperative AEs occurred in 3.3% (ACR) and 3.0% (no ACR; p = 0.945). In ACR cases, mean segmental lordosis changed from −2.8° (preoperative) to 16.4° (discharge; p < 0.001), 15.0° (3 months; p < 0.001) and 16.9° (12 months; p < 0.001), whereas this change was less in non-ACR cases [4.3° vs. 10.5° (discharge; p < 0.05), 10.9 (3 months; p < 0.05) and 10.4 (12 months; p > 0.05)]. Total lumbar lordosis increased from 27.8° to 45.2° (discharge; p < 0.001), 45.8° (3 months; p < 0.001) and 41.9° (12 months; p < 0.001) in ACR cases and from 37.4° to 46.7° (discharge; p < 0.01), 44.6° (3 months; n.s.) and 44.9° (12 months; n.s.) in non-ACR cases. Rates of AEs and clinical outcomes at 3 and 12 months were similar (all p > 0.05) and no pseudarthrosis at the LLIF level was noted.ConclusionsACR using an expandible LLIF interbody implant was safe, promoted solid fusion and restored significantly more segmental lordosis compared to LLIF without ALL release, which was maintained during follow-up.
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spelling doaj-art-dbd55a3ada8547fd83f4a9cec3f2c04d2024-12-09T06:28:33ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2024-12-011110.3389/fsurg.2024.14554451455445Indications, complications and outcomes of minimally-invasive lateral lumbar interbody fusion with anterior column realignment vs. standard LLIF using expandable interbody spacersGregor Fischer0Gregor Fischer1Linda Bättig2Linda Bättig3Thomas Schöfl4Thomas Schöfl5Ethan Schonfeld6Anand Veeravagu7Benjamin Martens8Benjamin Martens9Martin N. Stienen10Martin N. Stienen11Spine Center of Eastern Switzerland, Cantonal Hospital of St. Gallen & Medical School of St. Gallen, St. Gallen, SwitzerlandDepartment of Neurosurgery, Cantonal Hospital of St. Gallen & Medical School of St. Gallen, St. Gallen, SwitzerlandSpine Center of Eastern Switzerland, Cantonal Hospital of St. Gallen & Medical School of St. Gallen, St. Gallen, SwitzerlandDepartment of Neurosurgery, Cantonal Hospital of St. Gallen & Medical School of St. Gallen, St. Gallen, SwitzerlandSpine Center of Eastern Switzerland, Cantonal Hospital of St. Gallen & Medical School of St. Gallen, St. Gallen, SwitzerlandDepartment of Orthopedic Surgery, Cantonal Hospital of St. Gallen & Medical School of St. Gallen, St. Gallen, SwitzerlandDepartment of Neurosurgery, Stanford University, Stanford, CA, United StatesDepartment of Neurosurgery, Stanford University, Stanford, CA, United StatesSpine Center of Eastern Switzerland, Cantonal Hospital of St. Gallen & Medical School of St. Gallen, St. Gallen, SwitzerlandDepartment of Orthopedic Surgery, Cantonal Hospital of St. Gallen & Medical School of St. Gallen, St. Gallen, SwitzerlandSpine Center of Eastern Switzerland, Cantonal Hospital of St. Gallen & Medical School of St. Gallen, St. Gallen, SwitzerlandDepartment of Neurosurgery, Cantonal Hospital of St. Gallen & Medical School of St. Gallen, St. Gallen, SwitzerlandBackgroundAnterior column realignment (ACR), using a lateral lumbar or thoracic interbody fusion (LLIF) approach to release the anterior longitudinal ligament (ALL), is a powerful technique to increase segmental lordosis. We here report our experience with the use of expandible LLIF cages for ACR.MethodsRetrospective, single-center observational cohort study including consecutive patients treated by LLIF using an expandible interbody implant. Patients with ACR were compared to patients without ACR. Our outcomes include adverse events (AEs), radiological (segmental sagittal cobb angle, spinopelvic parameters) and clinical outcomes until 12 months postoperative.ResultsWe identified 503 patients, in which we performed LLIF at 732 levels. In 63 patients (12.5%) and 70 levels (9.6%) an expandable cage was used. Of those, in 30 patients (47.6%) and 30 levels, the ALL was released (42.8%). Age (mean 61.4 years), sex (57.1% female), comorbidities and further demographic features were similar, but patients in the ACR group had a higher anesthesiologic risk, were more frequently operated for degenerative deformity and had a more severely dysbalanced spine (all p < 0.05). ACR was most frequently done at L3/4 (36.7%) and L4/5 (23.3%), entailing multilevel fusions in 50% (3–7 levels) and long constructs in 26.7% (>7 levels). Intraoperative AEs occurred in 3.3% (ACR) and 3.0% (no ACR; p = 0.945). In ACR cases, mean segmental lordosis changed from −2.8° (preoperative) to 16.4° (discharge; p < 0.001), 15.0° (3 months; p < 0.001) and 16.9° (12 months; p < 0.001), whereas this change was less in non-ACR cases [4.3° vs. 10.5° (discharge; p < 0.05), 10.9 (3 months; p < 0.05) and 10.4 (12 months; p > 0.05)]. Total lumbar lordosis increased from 27.8° to 45.2° (discharge; p < 0.001), 45.8° (3 months; p < 0.001) and 41.9° (12 months; p < 0.001) in ACR cases and from 37.4° to 46.7° (discharge; p < 0.01), 44.6° (3 months; n.s.) and 44.9° (12 months; n.s.) in non-ACR cases. Rates of AEs and clinical outcomes at 3 and 12 months were similar (all p > 0.05) and no pseudarthrosis at the LLIF level was noted.ConclusionsACR using an expandible LLIF interbody implant was safe, promoted solid fusion and restored significantly more segmental lordosis compared to LLIF without ALL release, which was maintained during follow-up.https://www.frontiersin.org/articles/10.3389/fsurg.2024.1455445/fullACRLLIFexpandablecageinterbodyoutcomes
spellingShingle Gregor Fischer
Gregor Fischer
Linda Bättig
Linda Bättig
Thomas Schöfl
Thomas Schöfl
Ethan Schonfeld
Anand Veeravagu
Benjamin Martens
Benjamin Martens
Martin N. Stienen
Martin N. Stienen
Indications, complications and outcomes of minimally-invasive lateral lumbar interbody fusion with anterior column realignment vs. standard LLIF using expandable interbody spacers
Frontiers in Surgery
ACR
LLIF
expandable
cage
interbody
outcomes
title Indications, complications and outcomes of minimally-invasive lateral lumbar interbody fusion with anterior column realignment vs. standard LLIF using expandable interbody spacers
title_full Indications, complications and outcomes of minimally-invasive lateral lumbar interbody fusion with anterior column realignment vs. standard LLIF using expandable interbody spacers
title_fullStr Indications, complications and outcomes of minimally-invasive lateral lumbar interbody fusion with anterior column realignment vs. standard LLIF using expandable interbody spacers
title_full_unstemmed Indications, complications and outcomes of minimally-invasive lateral lumbar interbody fusion with anterior column realignment vs. standard LLIF using expandable interbody spacers
title_short Indications, complications and outcomes of minimally-invasive lateral lumbar interbody fusion with anterior column realignment vs. standard LLIF using expandable interbody spacers
title_sort indications complications and outcomes of minimally invasive lateral lumbar interbody fusion with anterior column realignment vs standard llif using expandable interbody spacers
topic ACR
LLIF
expandable
cage
interbody
outcomes
url https://www.frontiersin.org/articles/10.3389/fsurg.2024.1455445/full
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