Acute Myeloid Leukemia with Normal Cytogenetics and <i>NPM1</i>-Mutation: Impact of Mutation Topography on Outcomes

Acute Myeloid Leukemia with Normal Cytogenetics and <i>NPM1</i>-Mutation: Impact of Mutation Topography on Outcomes

<b>Background</b>: About half of adults with acute myeloid leukemia with normal cytogenetics (CN-AML) have <i>NPM1</i> mutations. There is controversy regarding their prognosis and best therapy. <b>Methods</b>: We studied 150 subjects with these features using tar...

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Bibliographic Details
Main Authors: Mingyue Zhao, Mingyue Liao, Robert Peter Gale, Meijie Zhang, Lixin Wu, Nan Yan, Lixia Liu, Jiayue Qin, Shanbo Cao, Yingjun Chang, Qian Jiang, Lanping Xu, Xiaohui Zhang, Xiaojun Huang, Hao Jiang, Guorui Ruan
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Biomedicines
Subjects:
acute myeloid leukemia
normal cytogenetics
<i>NPM1</i> mutation
risk stratification
Online Access:https://www.mdpi.com/2227-9059/12/12/2921
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