New benzimidazole-triazole glycoconjugates as anti-cancer agents and EGFR inhibitors
Abstract A new series of glycosyl heterocyclic scaffolds, 5a-10b with N-glycosidic linkage, were synthesized, starting with 2-acetyl-1H-benzimidazole as a precursor of the propargyl-derived substrates (2) and (3), which were then converted to the target 1,2,3-triazole glycosides (8a-10b) bearing unp...
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| Main Authors: | Aladdin M. Srour, Mohamed N. El-Bayaa, Ahmed Temirak, Asmaa L. Alanzy, Hanem M. Awad, Asmaa Saleh, Mahmoud G. Saleh, Wael A. El-Sayed |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
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| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-96675-3 |
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