Systematic characterization of all Toxoplasma gondii TBC domain-containing proteins identifies an essential regulator of Rab2 in the secretory pathway.

Toxoplasma gondii resides in its intracellular niche by employing a series of specialized secretory organelles that play roles in invasion, host cell manipulation, and parasite replication. Rab GTPases are major regulators of the parasite's secretory traffic that function as nucleotide-dependen...

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Bibliographic Details
Main Authors: Justin J Quan, Lachezar A Nikolov, Jihui Sha, James A Wohlschlegel, Isabelle Coppens, Peter J Bradley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-05-01
Series:PLoS Biology
Online Access:https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3002634&type=printable
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