Neuroprotective and intraocular pressure lowering effects of dual-functional memantine nitrate MN-08 on the experimental models of glaucoma

Abstract Glaucoma stands out as the primary cause of permanent blindness worldwide, marked by elevated intraocular pressure (IOP) and the deterioration of retinal ganglion cells (RGCs) within the optic nerve. This study aimed to investigate the therapeutic efficacy of MN-08, a novel memantine nitrat...

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Bibliographic Details
Main Authors: Huihui Hu, Liangmiao Wu, Xiaodie Hu, Minghua Wang, Yewei Sun, Gaoxiao Zhang, Yuqiang Wang, Peng Yi, Zaijun Zhang
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-06832-x
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