Pro-inflammatory interactions of streptolysin O toxin with human neutrophils in vitro

Pro-inflammatory interactions of streptolysin O toxin with human neutrophils in vitro

The recent global resurgence of severe infections caused by the Group A streptococcus (GAS) pathogen, Streptococcus pyogenes, has focused attention on this microbial pathogen, which produces an array of virulence factors, such as the pore-forming toxin, streptolysin O (SOT). Importantly, the interac...

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Bibliographic Details
Main Authors: D. Joseph, A. J. Theron, C. Feldman, R. Anderson, G. R. Tintinger
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Journal of Immunotoxicology
Subjects:
Streptolysin O toxin
neutrophils
cytosolic calcium
elastase
NETosis
reactive oxygen species
Online Access:https://www.tandfonline.com/doi/10.1080/1547691X.2024.2345152
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