Coordinated regulation of pH alkalinization by two transcription factors promotes fungal commensalism and pathogenicity

Coordinated regulation of pH alkalinization by two transcription factors promotes fungal commensalism and pathogenicity

Abstract As a clinically relevant opportunistic human fungal pathogen, Candida albicans is able to rapidly sense and adapt to changing microenvironments within the host, a process that is essential for its successful invasion and survival. Although studies have shown that the transcription factor St...

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Main Authors: Xinhua Huang, Guangsheng Chen, Lei Wu, Yun Zou, Luyao Zhang, Shanshan Li, Kunlin Li, Zaijie Jiang, Yuping Zhang, Xiaoqing Chen, Winnie Shum, Jianbiao Dai, Huichang Huang, Munika Moses, Xianwei Wu, Yuanyuan Wang, Tong Jiang, Zhiyi He, Qing Guo, Wenwen Xue, Hao Li, Changbin Chen
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62953-x
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