Rhodanine derivatives as potent anti-HIV and anti-HSV microbicides.

Rhodanine derivatives as potent anti-HIV and anti-HSV microbicides.

Although highly active antiretroviral therapies (HAART) remarkably increased life expectancy of HIV positive people, the rate of novel HIV-1 infections worldwide still represent a major concern. In this context, pre-exposure prophylaxis (PrEP) approaches such as vaginal microbicide gels topically re...

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Bibliographic Details
Main Authors: Cristina Tintori, Giulia Iovenitti, Elisa Rita Ceresola, Roberto Ferrarese, Claudio Zamperini, Annalaura Brai, Giulio Poli, Elena Dreassi, Valeria Cagno, David Lembo, Filippo Canducci, Maurizio Botta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://storage.googleapis.com/plos-corpus-prod/10.1371/journal.pone.0198478/1/pone.0198478.pdf?X-Goog-Algorithm=GOOG4-RSA-SHA256&X-Goog-Credential=wombat-sa%40plos-prod.iam.gserviceaccount.com%2F20210223%2Fauto%2Fstorage%2Fgoog4_request&X-Goog-Date=20210223T051511Z&X-Goog-Expires=3600&X-Goog-SignedHeaders=host&X-Goog-Signature=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