CircPTPN11 inhibits the replication of Coxsackievirus B5 through regulating the IFN-I pathway by targeting miR-152-3p/SIRPA axis

CircPTPN11 inhibits the replication of Coxsackievirus B5 through regulating the IFN-I pathway by targeting miR-152-3p/SIRPA axis

Coxsackievirus B5 (CVB5) is a major pathogen responsible for hand-foot-mouth disease, herpangina, and even severe death. The mechanisms underlying CVB5-induced diseases are not fully elucidated, and no specific antiviral treatments are currently available. Circular RNAs (circRNAs), a closed-loop mol...

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Bibliographic Details
Main Authors: Jingru Gao, Fan Yang, Jihong Zhang, Heng Yang, Wei Chen
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Virus Research
Subjects:
Coxsackieviruses group B5 (CVB5)
Circular RNAs (circRNAs)
IFN-I pathway
circRNA-miRNA-mRNA network
Hand, foot and mouth disease (HFMD)
Online Access:http://www.sciencedirect.com/science/article/pii/S0168170224002016
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