Antibacterial activity of promising nanostructured cesium oxide

Abstract As bacterial strains become increasingly resistant to antibiotics, many researchers are seeking novel, effective, and inexpensive antibiotics. Some nanomaterials have been suggested as potential candidates for use as novel antibacterial agents. In this study, cesium oxide nanoparticles were...

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Main Author: Wedam Alghazzawi
Format: Article
Language:English
Published: Springer 2025-08-01
Series:Discover Nano
Subjects:
Online Access:https://doi.org/10.1186/s11671-025-04327-2
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author Wedam Alghazzawi
author_facet Wedam Alghazzawi
author_sort Wedam Alghazzawi
collection DOAJ
description Abstract As bacterial strains become increasingly resistant to antibiotics, many researchers are seeking novel, effective, and inexpensive antibiotics. Some nanomaterials have been suggested as potential candidates for use as novel antibacterial agents. In this study, cesium oxide nanoparticles were synthesized and preliminarily investigated for their ability to inhibit the growth of bacteria. Although there are few studies on the applications of cesium oxide, it is possible that this oxide could have a substantial impact on biological activities. Cesium oxide nanoparticles were synthesized via fast calcination at 500 °C for 3 h. The composition and morphology of the prepared samples were characterized via X-ray diffraction, Fourier transform infrared spectroscopy, energy dispersive X-ray spectroscopy, and scanning electron microscope analysis, which verified the synthesis of cesium oxide nanoparticles. Agar well diffusion and minimum inhibitory concentration assays were used to study the antibacterial activity of cesium oxide nanoparticles against gram-positive and gram-negative bacteria. The experimental results provide preliminary support for developing cesium oxide nanostructures as antibacterial agents against a wide range of infections and diseases caused by bacteria. Graphical abstract
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institution Kabale University
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spelling doaj-art-db4abbb27bb74403923edea80bd6ffb82025-08-20T03:43:57ZengSpringerDiscover Nano2731-92292025-08-0120111210.1186/s11671-025-04327-2Antibacterial activity of promising nanostructured cesium oxideWedam Alghazzawi0Department of Biochemistry, Faculty of Sciences, King Abdulaziz UniversityAbstract As bacterial strains become increasingly resistant to antibiotics, many researchers are seeking novel, effective, and inexpensive antibiotics. Some nanomaterials have been suggested as potential candidates for use as novel antibacterial agents. In this study, cesium oxide nanoparticles were synthesized and preliminarily investigated for their ability to inhibit the growth of bacteria. Although there are few studies on the applications of cesium oxide, it is possible that this oxide could have a substantial impact on biological activities. Cesium oxide nanoparticles were synthesized via fast calcination at 500 °C for 3 h. The composition and morphology of the prepared samples were characterized via X-ray diffraction, Fourier transform infrared spectroscopy, energy dispersive X-ray spectroscopy, and scanning electron microscope analysis, which verified the synthesis of cesium oxide nanoparticles. Agar well diffusion and minimum inhibitory concentration assays were used to study the antibacterial activity of cesium oxide nanoparticles against gram-positive and gram-negative bacteria. The experimental results provide preliminary support for developing cesium oxide nanostructures as antibacterial agents against a wide range of infections and diseases caused by bacteria. Graphical abstracthttps://doi.org/10.1186/s11671-025-04327-2Cesium oxideNanoparticlesCalcinationAntibacterial activityAgar well diffusionMinimum inhibitory concentration
spellingShingle Wedam Alghazzawi
Antibacterial activity of promising nanostructured cesium oxide
Discover Nano
Cesium oxide
Nanoparticles
Calcination
Antibacterial activity
Agar well diffusion
Minimum inhibitory concentration
title Antibacterial activity of promising nanostructured cesium oxide
title_full Antibacterial activity of promising nanostructured cesium oxide
title_fullStr Antibacterial activity of promising nanostructured cesium oxide
title_full_unstemmed Antibacterial activity of promising nanostructured cesium oxide
title_short Antibacterial activity of promising nanostructured cesium oxide
title_sort antibacterial activity of promising nanostructured cesium oxide
topic Cesium oxide
Nanoparticles
Calcination
Antibacterial activity
Agar well diffusion
Minimum inhibitory concentration
url https://doi.org/10.1186/s11671-025-04327-2
work_keys_str_mv AT wedamalghazzawi antibacterialactivityofpromisingnanostructuredcesiumoxide