Antibiotic prophylaxis of acute postoperative endophthalmitis

<p> <b>V.P. Nikolaenko<sup>1,2</sup>, D.F. Belov<sup>1</sup></b> </p> <p> <b><sup>1</sup>City Multidisciplinary Hospital No. 2, St. Petersburg, Russian Federation</b> </p> <p> <b><sup>2</sup&g...

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Main Authors: V.P. Nikolaenko, D.F. Belov
Format: Article
Language:Russian
Published: Prime-Media 2021-12-01
Series:РМЖ "Клиническая офтальмология"
Online Access:http://clinopht.com/upload/iblock/eae/eaedccb38f1876a77f0fc5c0392d0c0f.pdf
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author V.P. Nikolaenko
D.F. Belov
author_facet V.P. Nikolaenko
D.F. Belov
author_sort V.P. Nikolaenko
collection DOAJ
description <p> <b>V.P. Nikolaenko<sup>1,2</sup>, D.F. Belov<sup>1</sup></b> </p> <p> <b><sup>1</sup>City Multidisciplinary Hospital No. 2, St. Petersburg, Russian Federation</b> </p> <p> <b><sup>2</sup>St. Petersburg State University, St. Petersburg, Russian Federation</b> </p> <p> <i>This paper reviews current aspects of antibacterial prophylaxis of acute endophthalmitis, a dangerous complication of cataract surgery. The lack of a common standard for preventing phaco infectious complications, a growing number of resistant bacterial strains, and legal aspects of the lack of some antibiotic formulations and routes of their administration with established efficacy in Russia account for the importance of this issue.</i> </p> <p> <i>The authors provide a list of primary causative agents of endophthalmitis and specify their antimicrobial susceptibility, highlight the importance of using antiseptics to prevent endophthalmitis, and describe in detail routes of administration of antibiotics, including conventional ones (subconjunctival injections, topical use) and whose actively promoted (intracameral, transzonular).</i> </p> <p> <i>In conclusion, the authors suggested a rational antimicrobial preventive algorithm for endophthalmitis after phaco based on the analysis of recent Russian and foreign published data and adapted to the Russian health care system.</i> </p> <p> <i><b>Keywords</b>: phacoemulsification, endophthalmitis, antiseptic, antibiotic, prophylaxis, antibacterial resistance, fluoroquinolones, aminoglycosides, povidone-iodine, intracameral administration.</i> </p> <p> <i><b>For citation: </b>Nikolaenko V.P., Belov D.F. Antibiotic prophylaxis of acute postoperative endophthalmitis. Russian Journal of Clinical Ophthalmology. 2021;21(4):220–226 (in Russ.). DOI: 10.32364/2311-7729-2021-21-4-220-226.</i> </p>
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spelling doaj-art-db49ccd1177c45ad9318c0ea4726ae0e2025-01-16T09:39:38ZrusPrime-MediaРМЖ "Клиническая офтальмология"2311-77292619-15712021-12-0121431368Antibiotic prophylaxis of acute postoperative endophthalmitisV.P. Nikolaenko0D.F. Belov1Russian Journal of Clinical Ophthalmology, Publisher of «Medicina-Inform» Address for correspondence: Russia, 105064, Moscow, P.O. Box 399Russian Journal of Clinical Ophthalmology, Publisher of «Medicina-Inform» Address for correspondence: Russia, 105064, Moscow, P.O. Box 399<p> <b>V.P. Nikolaenko<sup>1,2</sup>, D.F. Belov<sup>1</sup></b> </p> <p> <b><sup>1</sup>City Multidisciplinary Hospital No. 2, St. Petersburg, Russian Federation</b> </p> <p> <b><sup>2</sup>St. Petersburg State University, St. Petersburg, Russian Federation</b> </p> <p> <i>This paper reviews current aspects of antibacterial prophylaxis of acute endophthalmitis, a dangerous complication of cataract surgery. The lack of a common standard for preventing phaco infectious complications, a growing number of resistant bacterial strains, and legal aspects of the lack of some antibiotic formulations and routes of their administration with established efficacy in Russia account for the importance of this issue.</i> </p> <p> <i>The authors provide a list of primary causative agents of endophthalmitis and specify their antimicrobial susceptibility, highlight the importance of using antiseptics to prevent endophthalmitis, and describe in detail routes of administration of antibiotics, including conventional ones (subconjunctival injections, topical use) and whose actively promoted (intracameral, transzonular).</i> </p> <p> <i>In conclusion, the authors suggested a rational antimicrobial preventive algorithm for endophthalmitis after phaco based on the analysis of recent Russian and foreign published data and adapted to the Russian health care system.</i> </p> <p> <i><b>Keywords</b>: phacoemulsification, endophthalmitis, antiseptic, antibiotic, prophylaxis, antibacterial resistance, fluoroquinolones, aminoglycosides, povidone-iodine, intracameral administration.</i> </p> <p> <i><b>For citation: </b>Nikolaenko V.P., Belov D.F. Antibiotic prophylaxis of acute postoperative endophthalmitis. Russian Journal of Clinical Ophthalmology. 2021;21(4):220–226 (in Russ.). DOI: 10.32364/2311-7729-2021-21-4-220-226.</i> </p>http://clinopht.com/upload/iblock/eae/eaedccb38f1876a77f0fc5c0392d0c0f.pdf
spellingShingle V.P. Nikolaenko
D.F. Belov
Antibiotic prophylaxis of acute postoperative endophthalmitis
РМЖ "Клиническая офтальмология"
title Antibiotic prophylaxis of acute postoperative endophthalmitis
title_full Antibiotic prophylaxis of acute postoperative endophthalmitis
title_fullStr Antibiotic prophylaxis of acute postoperative endophthalmitis
title_full_unstemmed Antibiotic prophylaxis of acute postoperative endophthalmitis
title_short Antibiotic prophylaxis of acute postoperative endophthalmitis
title_sort antibiotic prophylaxis of acute postoperative endophthalmitis
url http://clinopht.com/upload/iblock/eae/eaedccb38f1876a77f0fc5c0392d0c0f.pdf
work_keys_str_mv AT vpnikolaenko antibioticprophylaxisofacutepostoperativeendophthalmitis
AT dfbelov antibioticprophylaxisofacutepostoperativeendophthalmitis