First PET Imaging Studies With Zn-Zinc Citrate in Healthy Human Participants and Patients With Alzheimer Disease

First PET Imaging Studies With Zn-Zinc Citrate in Healthy Human Participants and Patients With Alzheimer Disease

Abnormalities in zinc homeostasis are indicated in many human diseases, including Alzheimer disease (AD). 63 Zn-zinc citrate was developed as a positron emission tomography (PET) imaging probe of zinc transport and used in a first-in-human study in 6 healthy elderly individuals and 6 patients with c...

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Main Authors: Timothy R. DeGrado PhD, Bradley J. Kemp PhD, Mukesh K. Pandey PhD, Huailei Jiang PhD, Tina M. Gunderson MS, Logan R. Linscheid CNMT, Allison R. Woodwick CNMT, Daniel M. McConnell CNMT, Joel G. Fletcher MD, Geoffrey B. Johnson MD, PhD, Ronald C. Petersen MD, PhD, David S. Knopman MD, Val J. Lowe MD
Format: Article
Language:English
Published: SAGE Publishing 2016-12-01
Series:Molecular Imaging
Online Access:https://doi.org/10.1177/1536012116673793
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https://doi.org/10.1177/1536012116673793

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