Pulmonary Hypertension in Heart Failure Patients

The development of pulmonary hypertension (PH) in patients with heart failure is associated with increased morbidity and mortality. In this article, the authors examine recent changes to the definition of PH in the setting of left heart disease (PH-LHD), and discuss its epidemiology, pathophysiology...

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Main Authors: Sriram D Rao, Srinath Adusumalli, Jeremy A Mazurek
Format: Article
Language:English
Published: Radcliffe Medical Media 2020-04-01
Series:Cardiac Failure Review
Online Access:https://www.cfrjournal.com/articleindex/cfr.2019.09
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author Sriram D Rao
Srinath Adusumalli
Jeremy A Mazurek
author_facet Sriram D Rao
Srinath Adusumalli
Jeremy A Mazurek
author_sort Sriram D Rao
collection DOAJ
description The development of pulmonary hypertension (PH) in patients with heart failure is associated with increased morbidity and mortality. In this article, the authors examine recent changes to the definition of PH in the setting of left heart disease (PH-LHD), and discuss its epidemiology, pathophysiology and prognosis. They also explore the complexities of diagnosing PH-LHD and the current evidence for the use of medical therapies, promising clinical trials and the role of left ventricular assist device and transplantation.
format Article
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institution Kabale University
issn 2057-7540
2057-7559
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publishDate 2020-04-01
publisher Radcliffe Medical Media
record_format Article
series Cardiac Failure Review
spelling doaj-art-db06f54d4570423da67d8a9956157c1b2024-12-14T16:01:54ZengRadcliffe Medical MediaCardiac Failure Review2057-75402057-75592020-04-01610.15420/cfr.2019.09Pulmonary Hypertension in Heart Failure PatientsSriram D Rao0Srinath Adusumalli1Jeremy A Mazurek2Advanced Heart Failure/Transplantation Programme, Division of Cardiovascular Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USDepartment of Medicine, Division of Cardiovascular Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USAdvanced Heart Failure/Transplantation Programme, Division of Cardiovascular Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, US; Pulmonary Hypertension Programme, Division of Cardiovascular Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USThe development of pulmonary hypertension (PH) in patients with heart failure is associated with increased morbidity and mortality. In this article, the authors examine recent changes to the definition of PH in the setting of left heart disease (PH-LHD), and discuss its epidemiology, pathophysiology and prognosis. They also explore the complexities of diagnosing PH-LHD and the current evidence for the use of medical therapies, promising clinical trials and the role of left ventricular assist device and transplantation.https://www.cfrjournal.com/articleindex/cfr.2019.09
spellingShingle Sriram D Rao
Srinath Adusumalli
Jeremy A Mazurek
Pulmonary Hypertension in Heart Failure Patients
Cardiac Failure Review
title Pulmonary Hypertension in Heart Failure Patients
title_full Pulmonary Hypertension in Heart Failure Patients
title_fullStr Pulmonary Hypertension in Heart Failure Patients
title_full_unstemmed Pulmonary Hypertension in Heart Failure Patients
title_short Pulmonary Hypertension in Heart Failure Patients
title_sort pulmonary hypertension in heart failure patients
url https://www.cfrjournal.com/articleindex/cfr.2019.09
work_keys_str_mv AT sriramdrao pulmonaryhypertensioninheartfailurepatients
AT srinathadusumalli pulmonaryhypertensioninheartfailurepatients
AT jeremyamazurek pulmonaryhypertensioninheartfailurepatients