Development of potent humanized TNFα inhibitory nanobodies for therapeutic applications in TNFα-mediated diseases
Tumor necrosis factor-alpha (TNFα) is a key pro-inflammatory cytokine implicated in the pathogenesis of numerous inflammatory and autoimmune diseases, including rheumatoid arthritis, inflammatory bowel disease, and neurodegenerative disorders such as Alzheimer’s disease. Effective inhibition of TNFα...
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| Main Authors: | Tao Yin, Aubin Ramon, Matthew Greenig, Pietro Sormanni, Luciano D’Adamio |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2025-12-01
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| Series: | mAbs |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/19420862.2025.2498164 |
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