Quantitative Assessment of Photoneutron-induced Secondary Radiation Dose in Prostate Treatment Using an 18 MV Medical Linear Accelerator: A Monte Carlo Study
Purpose: This study aims to quantify the secondary radiation dose caused by photoneutrons during prostate cancer treatment using an 18 MV medical linear accelerator (LINAC) through Monte Carlo simulations and experimental validation. Methods: Monte Carlo simulations were performed using G4Linac_MT t...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2024-12-01
|
| Series: | Journal of Medical Physics |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/jmp.jmp_141_24 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841556604647899136 |
|---|---|
| author | Mustapha Assalmi Abdullah Alshreef EL Yamani Diaf Assia Arectout Nicholas Ade El Hassan El Berhdadi |
| author_facet | Mustapha Assalmi Abdullah Alshreef EL Yamani Diaf Assia Arectout Nicholas Ade El Hassan El Berhdadi |
| author_sort | Mustapha Assalmi |
| collection | DOAJ |
| description | Purpose:
This study aims to quantify the secondary radiation dose caused by photoneutrons during prostate cancer treatment using an 18 MV medical linear accelerator (LINAC) through Monte Carlo simulations and experimental validation.
Methods:
Monte Carlo simulations were performed using G4Linac_MT to model the 18 MV photon beam of an Elekta LINAC. The simulation results were validated against experimental measurements. Neutron characteristics, including penetration, cross-section interactions, Linear Energy Transfer (LET), and dose contributions, were analyzed using an adult male ICRP phantom. Prostate treatment scenarios involved 3D-CRT plans with 4-fields, 5-fields, and 7-fields. Specific absorbed fractions (SAFs) in various organs were also evaluated.
Results:
Simulation and experimental measurements showed strong agreement, with a dose error of approximately 0.74%, and 97% of dose points passed a 2%/2 mm gamma index. Intermediate neutrons constituted 87.05%, while 12.95% were fast neutrons. Neutron dose contributions were 0.63%, 0.33%, and 0.77% for the 3D-CRT 4-field, 5-field, and 7-field plans, respectively. SAF values decreased as neutron energy increased, highlighting reduced neutron interaction efficiency at higher energies.
Conclusions:
Monte Carlo simulation is a reliable approach for evaluating neutron dose contributions in high-energy X-ray LINACs. Optimization of treatment plans is essential to minimize neutron-induced dose contributions. |
| format | Article |
| id | doaj-art-daff97285cda4526af38f0fd514f2982 |
| institution | Kabale University |
| issn | 0971-6203 1998-3913 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Medical Physics |
| spelling | doaj-art-daff97285cda4526af38f0fd514f29822025-01-07T07:19:03ZengWolters Kluwer Medknow PublicationsJournal of Medical Physics0971-62031998-39132024-12-0149467368610.4103/jmp.jmp_141_24Quantitative Assessment of Photoneutron-induced Secondary Radiation Dose in Prostate Treatment Using an 18 MV Medical Linear Accelerator: A Monte Carlo StudyMustapha AssalmiAbdullah AlshreefEL Yamani DiafAssia ArectoutNicholas AdeEl Hassan El BerhdadiPurpose: This study aims to quantify the secondary radiation dose caused by photoneutrons during prostate cancer treatment using an 18 MV medical linear accelerator (LINAC) through Monte Carlo simulations and experimental validation. Methods: Monte Carlo simulations were performed using G4Linac_MT to model the 18 MV photon beam of an Elekta LINAC. The simulation results were validated against experimental measurements. Neutron characteristics, including penetration, cross-section interactions, Linear Energy Transfer (LET), and dose contributions, were analyzed using an adult male ICRP phantom. Prostate treatment scenarios involved 3D-CRT plans with 4-fields, 5-fields, and 7-fields. Specific absorbed fractions (SAFs) in various organs were also evaluated. Results: Simulation and experimental measurements showed strong agreement, with a dose error of approximately 0.74%, and 97% of dose points passed a 2%/2 mm gamma index. Intermediate neutrons constituted 87.05%, while 12.95% were fast neutrons. Neutron dose contributions were 0.63%, 0.33%, and 0.77% for the 3D-CRT 4-field, 5-field, and 7-field plans, respectively. SAF values decreased as neutron energy increased, highlighting reduced neutron interaction efficiency at higher energies. Conclusions: Monte Carlo simulation is a reliable approach for evaluating neutron dose contributions in high-energy X-ray LINACs. Optimization of treatment plans is essential to minimize neutron-induced dose contributions.https://journals.lww.com/10.4103/jmp.jmp_141_24absorbed fractionsmedical linear acceleratormonte carlo simulationneutron energyphotoneutronsprostate treatmentsecondary radiation dose |
| spellingShingle | Mustapha Assalmi Abdullah Alshreef EL Yamani Diaf Assia Arectout Nicholas Ade El Hassan El Berhdadi Quantitative Assessment of Photoneutron-induced Secondary Radiation Dose in Prostate Treatment Using an 18 MV Medical Linear Accelerator: A Monte Carlo Study Journal of Medical Physics absorbed fractions medical linear accelerator monte carlo simulation neutron energy photoneutrons prostate treatment secondary radiation dose |
| title | Quantitative Assessment of Photoneutron-induced Secondary Radiation Dose in Prostate Treatment Using an 18 MV Medical Linear Accelerator: A Monte Carlo Study |
| title_full | Quantitative Assessment of Photoneutron-induced Secondary Radiation Dose in Prostate Treatment Using an 18 MV Medical Linear Accelerator: A Monte Carlo Study |
| title_fullStr | Quantitative Assessment of Photoneutron-induced Secondary Radiation Dose in Prostate Treatment Using an 18 MV Medical Linear Accelerator: A Monte Carlo Study |
| title_full_unstemmed | Quantitative Assessment of Photoneutron-induced Secondary Radiation Dose in Prostate Treatment Using an 18 MV Medical Linear Accelerator: A Monte Carlo Study |
| title_short | Quantitative Assessment of Photoneutron-induced Secondary Radiation Dose in Prostate Treatment Using an 18 MV Medical Linear Accelerator: A Monte Carlo Study |
| title_sort | quantitative assessment of photoneutron induced secondary radiation dose in prostate treatment using an 18 mv medical linear accelerator a monte carlo study |
| topic | absorbed fractions medical linear accelerator monte carlo simulation neutron energy photoneutrons prostate treatment secondary radiation dose |
| url | https://journals.lww.com/10.4103/jmp.jmp_141_24 |
| work_keys_str_mv | AT mustaphaassalmi quantitativeassessmentofphotoneutroninducedsecondaryradiationdoseinprostatetreatmentusingan18mvmedicallinearacceleratoramontecarlostudy AT abdullahalshreef quantitativeassessmentofphotoneutroninducedsecondaryradiationdoseinprostatetreatmentusingan18mvmedicallinearacceleratoramontecarlostudy AT elyamanidiaf quantitativeassessmentofphotoneutroninducedsecondaryradiationdoseinprostatetreatmentusingan18mvmedicallinearacceleratoramontecarlostudy AT assiaarectout quantitativeassessmentofphotoneutroninducedsecondaryradiationdoseinprostatetreatmentusingan18mvmedicallinearacceleratoramontecarlostudy AT nicholasade quantitativeassessmentofphotoneutroninducedsecondaryradiationdoseinprostatetreatmentusingan18mvmedicallinearacceleratoramontecarlostudy AT elhassanelberhdadi quantitativeassessmentofphotoneutroninducedsecondaryradiationdoseinprostatetreatmentusingan18mvmedicallinearacceleratoramontecarlostudy |