Hair Loss Associated with Sertraline: A Case Report
Sertraline is classified as a selective serotonin reuptake inhibitor (SSRI) that is extensively employed in the management of a range of psychiatric conditions, encompassing major depressive disorder and anxiety disorders. While the overall incidence of hair loss is not extensively documented, it i...
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Tehran University of Medical Sciences
2024-12-01
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| Series: | Case Reports in Clinical Practice |
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| Online Access: | https://crcp.tums.ac.ir/index.php/crcp/article/view/997 |
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| author | Seyed Hamzeh Hosseini Hamed Ghazvini Seyedeh Masoumeh Seyedhosseini Tamijani Raheleh Rafaiee |
| author_facet | Seyed Hamzeh Hosseini Hamed Ghazvini Seyedeh Masoumeh Seyedhosseini Tamijani Raheleh Rafaiee |
| author_sort | Seyed Hamzeh Hosseini |
| collection | DOAJ |
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Sertraline is classified as a selective serotonin reuptake inhibitor (SSRI) that is extensively employed in the management of a range of psychiatric conditions, encompassing major depressive disorder and anxiety disorders. While the overall incidence of hair loss is not extensively documented, it is recognized as a possible
cutaneous reaction to SSRIs, including sertraline. In the present study, we report the case of a 16-year-old Iranian female of Persian ethnicity who had been treated for panic disorder. She developed severe hair loss
two weeks post-initiation of treatment with sertraline 50 mg per day. She stopped the medication after two months when she had lost 50% of her hair. The exact mechanism remains unclear, but it is suggested that SSRIs like sertraline may induce hair loss by pushing hair follicles into the telogen phase prematurely, leading to diffuse hair shedding. Management typically involves dose adjustment or discontinuation of sertraline, which has been shown to resolve hair loss in multiple cases. Understanding this phenomenon is crucial for both patients and healthcare providers. Although rare, this side effect can considerably affect a patient’s overall quality of life and compliance with therapeutic regimens.
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| format | Article |
| id | doaj-art-da635a136a8949abbfe9dff5ab18ae26 |
| institution | Kabale University |
| issn | 2538-2683 2538-2691 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Case Reports in Clinical Practice |
| spelling | doaj-art-da635a136a8949abbfe9dff5ab18ae262025-01-06T08:36:48ZengTehran University of Medical SciencesCase Reports in Clinical Practice2538-26832538-26912024-12-019310.18502/crcp.v9i3.17241Hair Loss Associated with Sertraline: A Case ReportSeyed Hamzeh Hosseini0Hamed Ghazvini1Seyedeh Masoumeh Seyedhosseini Tamijani2Raheleh Rafaiee3Department of Psychiatry, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.Department of Neuroscience, School of Advanced Technologies in Medicine, Mazandaran University of Medical Sciences, Sari, Iran.Psychiatry and Behavioral Sciences Research Center, Addiction Institute, Mazandaran University of Medical Sciences, Sari, Iran.Department of Neuroscience, School of Advanced Technologies in Medicine, Mazandaran University of Medical Sciences, Sari, Iran. Sertraline is classified as a selective serotonin reuptake inhibitor (SSRI) that is extensively employed in the management of a range of psychiatric conditions, encompassing major depressive disorder and anxiety disorders. While the overall incidence of hair loss is not extensively documented, it is recognized as a possible cutaneous reaction to SSRIs, including sertraline. In the present study, we report the case of a 16-year-old Iranian female of Persian ethnicity who had been treated for panic disorder. She developed severe hair loss two weeks post-initiation of treatment with sertraline 50 mg per day. She stopped the medication after two months when she had lost 50% of her hair. The exact mechanism remains unclear, but it is suggested that SSRIs like sertraline may induce hair loss by pushing hair follicles into the telogen phase prematurely, leading to diffuse hair shedding. Management typically involves dose adjustment or discontinuation of sertraline, which has been shown to resolve hair loss in multiple cases. Understanding this phenomenon is crucial for both patients and healthcare providers. Although rare, this side effect can considerably affect a patient’s overall quality of life and compliance with therapeutic regimens. https://crcp.tums.ac.ir/index.php/crcp/article/view/997Hair lossSertraline |
| spellingShingle | Seyed Hamzeh Hosseini Hamed Ghazvini Seyedeh Masoumeh Seyedhosseini Tamijani Raheleh Rafaiee Hair Loss Associated with Sertraline: A Case Report Case Reports in Clinical Practice Hair loss Sertraline |
| title | Hair Loss Associated with Sertraline: A Case Report |
| title_full | Hair Loss Associated with Sertraline: A Case Report |
| title_fullStr | Hair Loss Associated with Sertraline: A Case Report |
| title_full_unstemmed | Hair Loss Associated with Sertraline: A Case Report |
| title_short | Hair Loss Associated with Sertraline: A Case Report |
| title_sort | hair loss associated with sertraline a case report |
| topic | Hair loss Sertraline |
| url | https://crcp.tums.ac.ir/index.php/crcp/article/view/997 |
| work_keys_str_mv | AT seyedhamzehhosseini hairlossassociatedwithsertralineacasereport AT hamedghazvini hairlossassociatedwithsertralineacasereport AT seyedehmasoumehseyedhosseinitamijani hairlossassociatedwithsertralineacasereport AT rahelehrafaiee hairlossassociatedwithsertralineacasereport |